About
Sartel LN is a fixed-dose combination medication specifically formulated for the comprehensive management of essential hypertension. It comprises two distinct antihypertensive agents: Telmisartan, an angiotensin II receptor blocker (ARB), and Amlodipine, a dihydropyridine calcium channel blocker (CCB). This synergistic combination is particularly beneficial for patients whose blood pressure remains inadequately controlled with monotherapy, or as an initial therapeutic approach when a multi-drug regimen is anticipated to be necessary. Telmisartan exerts its effect by selectively blocking the binding of angiotensin II to its AT1 receptors, leading to vasodilation, reduced aldosterone secretion, and decreased blood pressure. Amlodipine, on the other hand, relaxes vascular smooth muscle cells, primarily in the peripheral arteries, resulting in peripheral vasodilation and a reduction in systemic vascular resistance. The combined action of these two agents provides robust and sustained blood pressure control, effectively mitigating the risks of serious cardiovascular events such as stroke, myocardial infarction, and heart failure, thereby improving long-term patient outcomes.
Uses
- Treatment of essential hypertension.
- Blood pressure control in patients not responding to monotherapy.
- Initial therapy for moderate to severe hypertension.
- Prevention of cardiovascular events related to high blood pressure.
Directions For Use
Take one tablet orally once daily, with or without food, preferably at the same time each day.
Benefits
- Provides effective blood pressure reduction.
- Offers dual mechanism of action for comprehensive control.
- Reduces risk of cardiovascular morbidity and mortality.
- Convenient once-daily dosing.
- Well-tolerated in many patients.
- May improve patient adherence due to combination.
Side Effects
- Dizziness
- Headache
- Peripheral edema (swelling of ankles/feet)
- Fatigue
- Nausea
- Flushing
- Palpitations
- Abdominal pain
- Hypotension
- Bradycardia (slow heart rate)
- Cough (less common than ACE inhibitors)
- Hyperkalemia (rare)
Safety Measures
- Alcohol - Alcohol can increase the hypotensive effect and risk of dizziness. Use with caution and moderate intake.
- Pregnancy - Contraindicated during the second and third trimesters due to fetal toxicity. Avoid in first trimester.
- Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk.
- Liver - Use with caution in patients with hepatic impairment. Dosage adjustment may be necessary.
- Kidney - Use with caution in patients with renal impairment. Monitor kidney function and potassium levels.
- Lung - Generally safe for use in patients with lung conditions. No specific contraindications related to lung function.
Disclaimer
MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.
Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
| Shipping Cost |
|
| Shop Location | Assam, India |
No comments found for this product. Be the first to comment!