CILNIKEM 10MG TAB 10 S

About

CILNIKEM 10MG TAB contains Cilnidipine, a unique dihydropyridine calcium channel blocker distinguished by its dual inhibitory action on both L-type and N-type calcium channels. This mechanism leads to effective peripheral vasodilation by reducing calcium influx into vascular smooth muscle cells, thereby lowering systemic vascular resistance and blood pressure. The additional N-type channel blockade is significant as it helps to suppress sympathetic nervous system overactivity, which can contribute to hypertension and target organ damage. This dual action provides a comprehensive approach to blood pressure control, reducing the workload on the heart and improving arterial compliance. Cilnidipine is primarily indicated for the long-term management of essential hypertension, offering sustained antihypertensive effects and potential benefits in preventing cardiovascular complications.

Uses

• Treatment of essential hypertension.
• Management of high blood pressure.
• Prevention of cardiovascular events associated with hypertension.
• Reduction of sympathetic nervous system activity.

Directions For Use

Take one tablet orally once daily, preferably at the same time each day, with or without food, as directed by your physician.

Benefits

• Effectively lowers high blood pressure.
• Reduces the risk of heart attack and stroke.
• Provides sustained blood pressure control.
• May reduce sympathetic overactivity.
• Generally well-tolerated.
• Improves cardiovascular outcomes.

Side Effects

• Headache
• Dizziness
• Flushing
• Palpitations
• Edema (swelling of ankles/feet)
• Fatigue
• Nausea
• Abdominal discomfort
• Gingival hyperplasia (gum overgrowth)
• Rash
• Hypotension (low blood pressure)
• Tachycardia (fast heart rate)

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can enhance the blood pressure-lowering effect and increase the risk of dizziness and drowsiness.
• Pregnancy - Not recommended during pregnancy unless clearly necessary and potential benefits outweigh risks. Consult your doctor.
• Breastfeeding - Not recommended during breastfeeding as it may pass into breast milk. Consult your doctor.
• Liver - Use with caution in patients with liver impairment as metabolism may be affected, potentially leading to increased drug levels. Dose adjustment may be necessary.
• Kidney - Use with caution in patients with severe kidney impairment. Dose adjustment may be required.
• Lung - Generally safe for use in patients with lung conditions; no specific contraindications related to respiratory function.

Disclaimer

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