SEVIX 400 TAB 10

About

SEVIX 400 TAB contains Levetiracetam 400mg, an anti-epileptic medication utilized for the management of various seizure disorders. Its mechanism of action is distinct from other antiepileptic drugs, involving the modulation of synaptic vesicle protein 2A (SV2A), which plays a role in neurotransmitter release. By binding to SV2A, Levetiracetam is thought to inhibit abnormal neuronal firing and prevent the spread of seizure activity without significantly impacting normal brain function. It is indicated for use as monotherapy or adjunctive therapy in adults and children with partial-onset seizures, and as adjunctive therapy for myoclonic seizures in juvenile myoclonic epilepsy and primary generalized tonic-clonic seizures. Levetiracetam is known for its favorable pharmacokinetic profile, including minimal metabolism by the liver and predominantly renal excretion, which contributes to a lower risk of drug-drug interactions.

Uses

• Treatment of partial-onset seizures in adults and children
• Adjunctive therapy for myoclonic seizures
• Adjunctive therapy for primary generalized tonic-clonic seizures
• Long-term management of epilepsy

Directions For Use

Take the tablet orally with or without food, as prescribed by your doctor. Do not discontinue treatment suddenly without medical advice.

Benefits

• Effective in controlling a broad spectrum of seizures
• Well-tolerated by most patients
• Minimal drug-drug interaction potential
• Flexible dosing for various indications
• Improves seizure control and patient well-being
• Can be used in combination with other AEDs

Side Effects

• Drowsiness or somnolence
• Dizziness
• Headache
• Fatigue
• Behavioral changes (e.g., irritability, aggression)
• Nausea
• Diarrhea
• Loss of appetite
• Weakness (asthenia)
• Upper respiratory tract infection
• Double vision
• Mood changes

Safety Measures

• Alcohol - Alcohol can intensify central nervous system depression and dizziness. It is advisable to avoid or limit alcohol intake.
• Pregnancy - Levetiracetam should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Discuss with your doctor.
• Breastfeeding - Levetiracetam is present in breast milk. Breastfeeding mothers should monitor infants for sedation or irritability. Consult a healthcare professional.
• Liver - No specific dose adjustment is generally required for patients with hepatic impairment, as it is primarily excreted unchanged by the kidneys.
• Kidney - Dose reduction is necessary for patients with impaired renal function, as the drug is predominantly eliminated via the kidneys.
• Lung - This medication is not typically associated with direct adverse effects on respiratory function.

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