SEVLAREN-800 10

About

Sevlaren-800 contains sevelamer, a non-calcium, non-aluminum phosphate binder used to control serum phosphorus levels in patients with chronic kidney disease (CKD) who are on dialysis. In CKD, impaired kidney function leads to an accumulation of phosphate in the blood, a condition known as hyperphosphatemia. Elevated phosphate levels can contribute to various complications, including secondary hyperparathyroidism, renal osteodystrophy, and increased cardiovascular risk. Sevelamer works by binding to dietary phosphate in the gastrointestinal tract, forming an insoluble complex that is then excreted in the feces, thereby preventing its absorption into the bloodstream.

By effectively reducing serum phosphate, Sevlaren-800 helps to mitigate the progression of bone disease and calcification of soft tissues and blood vessels, which are common and serious complications in dialysis patients. Unlike calcium-based binders, sevelamer does not contribute to calcium load, making it a preferred option for patients at risk of hypercalcemia. Adherence to the prescribed dosage with meals is crucial for its efficacy in managing this critical aspect of CKD management.

Uses

• Control of serum phosphorus in adult patients with CKD on dialysis.
• Prevention of hyperphosphatemia-related complications.
• Management of secondary hyperparathyroidism in CKD.
• Reduction of cardiovascular risk associated with high phosphate.

Directions For Use

Take the prescribed number of tablets with meals, as directed by your nephrologist. Do not crush or chew the tablets.

Benefits

• Effectively lowers serum phosphate levels.
• Reduces the risk of renal osteodystrophy.
• Does not contribute to systemic calcium load.
• Helps prevent vascular calcification.
• Improves overall bone health in CKD patients.
• Supports better management of chronic kidney disease.

Side Effects

• Nausea
• Vomiting
• Diarrhea
• Constipation
• Abdominal pain
• Indigestion
• Flatulence
• Dyspepsia
• Headache
• Pruritus (itching)
• Peritonitis (in dialysis patients, rare)
• Bowel obstruction (rare)

Safety Measures

• Alcohol - No direct interaction, but alcohol can worsen overall health in CKD patients; moderation is advised.
• Pregnancy - Consult a doctor; use only if clearly needed and potential benefits outweigh risks.
• Breastfeeding - Consult a doctor; it is unknown if sevelamer is excreted in human milk.
• Liver - Generally safe for use in patients with liver conditions, as it is not systemically absorbed.
• Kidney - Specifically indicated for patients with chronic kidney disease on dialysis; close monitoring by a nephrologist is essential.
• Lung - No specific contraindications related to lung conditions; generally considered safe.

Disclaimer

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