VELACAR-400 10

About

Velacar-400 is a non-calcium, non-aluminum phosphate binder indicated for the management of hyperphosphatemia in patients with chronic kidney disease (CKD) who are undergoing dialysis. Hyperphosphatemia is a common and serious complication of CKD, characterized by elevated serum phosphate levels due to the kidneys' inability to adequately excrete phosphate. This condition significantly contributes to the development of secondary hyperparathyroidism, renal osteodystrophy, and an increased risk of cardiovascular events. Velacar-400 works by binding to dietary phosphate in the gastrointestinal tract, forming insoluble complexes that are subsequently excreted in the feces, thereby preventing its absorption into the bloodstream. This mechanism effectively lowers serum phosphate concentrations without contributing to calcium or aluminum overload.

Regular administration of Velacar-400, as an integral part of a comprehensive treatment regimen that includes dietary phosphate restriction, is crucial for maintaining phosphate balance, mitigating bone and mineral disorders, and improving long-term outcomes for CKD patients. Its non-systemic action and favorable safety profile make it a valuable therapeutic option. Adherence to the prescribed dosage and dietary recommendations is paramount for achieving optimal therapeutic efficacy and preventing the severe complications associated with uncontrolled phosphate levels.

Uses

• Management of hyperphosphatemia in CKD patients on dialysis.
• Control of serum phosphate levels.
• Prevention of renal osteodystrophy.
• Support for mineral and bone disorder management.

Directions For Use

Take Velacar-400 orally with meals. Do not crush, chew, or break the tablets; swallow them whole with water.

Benefits

• Effectively controls elevated serum phosphate levels.
• Reduces the risk of secondary hyperparathyroidism.
• Helps prevent the progression of renal osteodystrophy.
• Contributes to improved cardiovascular outcomes in CKD.
• Non-calcium and non-aluminum based.
• Generally well-tolerated with proper administration.

Side Effects

• Nausea
• Vomiting
• Diarrhea
• Constipation
• Abdominal pain
• Dyspepsia
• Flatulence
• Headache
• Dizziness
• Pruritus
• Muscle spasms
• Joint pain

Safety Measures

• Alcohol - No direct interaction, but excessive alcohol intake can worsen kidney disease and overall health, which may impact treatment efficacy.
• Pregnancy - Consult your doctor before use if pregnant. Use only if the potential benefit justifies the potential risk to the fetus.
• Breastfeeding - Consult your doctor before use if breastfeeding. It is unknown if Velacar-400 is excreted in human milk.
• Liver - Use with caution in patients with severe liver impairment. No specific dose adjustment is typically needed, but monitor for adverse effects.
• Kidney - Velacar-400 is primarily used in patients with chronic kidney disease. Monitor serum phosphate, calcium, and parathyroid hormone levels regularly.
• Lung - No specific contraindications related to lung conditions are typically noted, but always inform your doctor of all medical conditions.

Disclaimer

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