About
This combination therapy provides a robust approach to managing benign prostatic hyperplasia (BPH) by integrating the rapid symptomatic relief of Silodosin with the long-term prostate volume reduction achieved by Dutasteride. Silodosin, a highly selective alpha-1A adrenergic receptor antagonist, quickly relaxes the smooth muscles in the prostate, bladder base, and prostatic urethra, thereby improving urine flow and alleviating bothersome urinary symptoms such as urgency, frequency, and a weak stream. Dutasteride, a dual 5-alpha-reductase inhibitor, works by inhibiting both type 1 and type 2 isoforms of 5-alpha-reductase, which are responsible for converting testosterone to dihydrotestosterone (DHT).
By reducing DHT levels, Dutasteride effectively shrinks the enlarged prostate gland over time, addressing the root cause of BPH, preventing disease progression, and significantly lowering the risk of acute urinary retention and the need for surgical intervention. This combined treatment offers both immediate symptomatic improvement and sustained therapeutic benefits for BPH.
Uses
- Treatment of moderate to severe symptoms of benign prostatic hyperplasia (BPH).
- Reduction of the risk of acute urinary retention (AUR).
- Reduction of the need for BPH-related surgery.
- Improvement of urinary flow and reduction of prostate volume.
Directions For Use
Take one capsule orally once daily with a meal. Swallow the capsule whole; do not chew or open.
Benefits
- Offers rapid symptomatic improvement.
- Effectively shrinks the enlarged prostate.
- Reduces the risk of BPH progression.
- Decreases the incidence of acute urinary retention.
- May reduce the need for surgical intervention.
- Provides comprehensive long-term BPH management.
Side Effects
- Retrograde ejaculation
- Dizziness
- Orthostatic hypotension
- Decreased libido
- Erectile dysfunction
- Breast tenderness/enlargement
- Headache
- Nasal congestion
- Nausea
- Diarrhea
- Allergic reactions (rash, itching)
- Depressed mood
Safety Measures
- Alcohol - Alcohol can intensify the hypotensive effects of silodosin, increasing the risk of dizziness and fainting. Avoid or limit alcohol.
- Pregnancy - Contraindicated in pregnant women due to the risk of external genital abnormalities in a male fetus.
- Breastfeeding - Not indicated for use in women; should not be used by breastfeeding mothers.
- Liver - Contraindicated in patients with severe hepatic impairment. Use with caution in moderate impairment.
- Kidney - Contraindicated in patients with severe renal impairment. Dosage adjustment is required for moderate renal impairment.
- Lung - Generally considered safe for patients with lung conditions; monitor for any unusual respiratory symptoms.
Disclaimer
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| Shop Location | Assam, India |
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