TAMODEX 20MG TAB 1X10

About

Tamoxifen is a selective estrogen receptor modulator (SERM) that plays a pivotal role in the management and prevention of hormone receptor-positive breast cancer. Its primary mechanism of action involves competitively binding to estrogen receptors within breast cancer cells, effectively blocking the proliferative effects of estrogen on these cells. This anti-estrogenic action in breast tissue helps to inhibit tumor growth and reduce the risk of cancer recurrence. Conversely, tamoxifen exhibits estrogen-like effects in other tissues, such as bone, where it can help maintain bone density, and in the uterus.

This unique pharmacological profile makes tamoxifen a highly effective and widely utilized agent in both adjuvant therapy following primary treatment and for advanced or metastatic disease, significantly improving long-term outcomes for patients with estrogen receptor-positive breast cancer.

Uses

• Adjuvant treatment of hormone receptor-positive breast cancer
• Metastatic hormone receptor-positive breast cancer
• Reduction in incidence of invasive breast cancer in high-risk women
• Reduction in incidence of contralateral breast cancer

Directions For Use

Take orally once or twice daily, with or without food, as prescribed by your doctor. Swallow the tablet whole.

Benefits

• Reduces breast cancer recurrence risk.
• Effective in both early and advanced disease.
• Can prevent breast cancer in high-risk women.
• Improves overall survival in ER+ breast cancer.
• May have beneficial effects on bone density.
• Well-established and widely studied therapy.

Side Effects

• Hot flashes
• Nausea
• Vaginal discharge
• Fluid retention
• Fatigue
• Mood changes
• Endometrial cancer (rare, serious)
• Thromboembolic events (DVT, PE, stroke - rare, serious)
• Cataracts
• Uterine fibroids
• Skin rash
• Hair thinning

Safety Measures

• Alcohol - No direct interaction, but excessive alcohol may increase the risk of liver side effects. Discuss with your doctor.
• Pregnancy - Contraindicated in pregnancy due to potential for fetal harm. Effective non-hormonal contraception is required.
• Breastfeeding - Not recommended during breastfeeding due to potential for serious adverse effects in the infant.
• Liver - Use with caution in patients with pre-existing liver impairment. Monitor liver function periodically.
• Kidney - No specific dose adjustment is typically required for kidney impairment.
• Lung - Generally safe for use in patients with lung conditions. No specific lung-related contraindications.

Disclaimer

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