About
Telmisartan is an angiotensin II receptor blocker (ARB) specifically indicated for the treatment of essential hypertension. It functions by selectively blocking the AT1 receptor, which is responsible for mediating the physiological effects of angiotensin II, including vasoconstriction and the stimulation of aldosterone secretion. By inhibiting these actions, Telmisartan promotes vasodilation, reduces systemic vascular resistance, and consequently lowers blood pressure. Its favorable pharmacokinetic profile, characterized by a long elimination half-life, supports once-daily administration, ensuring consistent and effective blood pressure control throughout the day. This medication serves as a foundational therapy for managing high blood pressure, helping to prevent the progression of cardiovascular disease and reducing the long-term risks associated with uncontrolled hypertension, such as stroke, heart attack, and kidney damage.
Uses
- Treatment of essential hypertension.
- Initial management of high blood pressure.
- Long-term blood pressure control.
- Reduction of cardiovascular risk in appropriate patients.
Directions For Use
Take one tablet orally once daily, with or without food, as directed by your healthcare provider.
Benefits
- Effective in lowering blood pressure.
- Provides 24-hour blood pressure control.
- Reduces risk of cardiovascular complications.
- Generally well-tolerated.
- Convenient once-daily dosing.
- Suitable for monotherapy or combination therapy.
Side Effects
- Dizziness
- Headache
- Fatigue
- Hypotension
- Back pain
- Diarrhea
- Nausea
- Upper respiratory tract infection
- Cough (less common than ACE inhibitors)
- Hyperkalemia (rare)
- Angioedema (very rare)
- Syncope
Safety Measures
- Alcohol - Limit alcohol intake as it can enhance the blood pressure-lowering effect and increase dizziness.
- Pregnancy - Contraindicated during the second and third trimesters of pregnancy due to potential fetal harm.
- Breastfeeding - Not recommended; consult your doctor as it may pass into breast milk.
- Liver - Use with caution in patients with mild to moderate hepatic impairment; severe impairment is a contraindication.
- Kidney - Use with caution in patients with renal artery stenosis or severe renal impairment; monitor kidney function closely.
- Lung - Generally safe for use in patients with lung conditions.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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