About
Telmisartan is a highly effective angiotensin II receptor blocker (ARB) primarily indicated for the treatment of essential hypertension. It operates by selectively blocking the AT1 receptor, preventing the binding of angiotensin II, a powerful hormone responsible for vasoconstriction and aldosterone release. This blockade results in the relaxation of blood vessels, a reduction in systemic vascular resistance, and a subsequent decrease in blood pressure. Telmisartan is known for its long duration of action, allowing for convenient once-daily dosing, which significantly enhances patient adherence. Beyond its primary role in blood pressure management, Telmisartan is also prescribed for the reduction of cardiovascular morbidity and mortality in adults at high risk, including those with established atherosclerotic cardiovascular disease or type 2 diabetes with target organ damage. Its protective effects extend to reducing the incidence of stroke, myocardial infarction, and cardiovascular death.
Uses
- Treatment of essential hypertension.
- Reduction of cardiovascular risk in high-risk patients.
- Prevention of stroke and myocardial infarction.
- Management of diabetic nephropathy in type 2 diabetes.
Directions For Use
Take one tablet orally once daily, with or without food, as directed by your healthcare provider.
Benefits
- Effective blood pressure control.
- Reduces risk of major cardiovascular events.
- Long-lasting effect for once-daily dosing.
- Well-tolerated in most patients.
- Protects against target organ damage.
- Suitable for patients intolerant to ACE inhibitors.
Side Effects
- Dizziness
- Headache
- Fatigue
- Hypotension
- Back pain
- Diarrhea
- Nausea
- Upper respiratory tract infection
- Cough (less common than ACE inhibitors)
- Hyperkalemia (rare)
- Angioedema (very rare)
- Syncope
Safety Measures
- Alcohol - Limit alcohol intake as it can enhance the blood pressure-lowering effect and increase dizziness.
- Pregnancy - Contraindicated during the second and third trimesters of pregnancy due to potential fetal harm.
- Breastfeeding - Not recommended; consult your doctor as it may pass into breast milk.
- Liver - Use with caution in patients with mild to moderate hepatic impairment; severe impairment is a contraindication.
- Kidney - Use with caution in patients with renal artery stenosis or severe renal impairment; monitor kidney function closely.
- Lung - Generally safe for use in patients with lung conditions.
Disclaimer
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