TETAN CT 12.5 TAB 10 S

About

TETAN CT 12.5 TAB is a combination antihypertensive medication containing Telmisartan and Chlorthalidone. Telmisartan, an angiotensin II receptor blocker (ARB), works by selectively blocking the AT1 receptor, preventing angiotensin II from causing vasoconstriction and aldosterone release, thereby lowering blood pressure. Chlorthalidone is a long-acting thiazide-like diuretic that enhances the excretion of sodium and water by the kidneys, leading to a reduction in blood volume and peripheral vascular resistance. The synergistic action of these two agents provides comprehensive and effective control of elevated blood pressure, making it a valuable option for patients whose blood pressure is not adequately controlled by monotherapy.

This combination therapy is particularly effective in managing essential hypertension, leveraging two distinct mechanisms to achieve optimal blood pressure reduction. Telmisartan offers sustained blood pressure control and has a favorable cardiovascular safety profile, while Chlorthalidone contributes to volume reduction and has a prolonged duration of action. The 12.5mg dose of Chlorthalidone is a standard therapeutic dose, balancing efficacy with tolerability. Regular monitoring of blood pressure, electrolytes, and renal function is crucial during treatment to ensure efficacy and safety, optimizing cardiovascular outcomes for patients and minimizing potential adverse effects associated with long-term use.

Uses

• Treatment of essential hypertension
• Management of high blood pressure
• Reduction of cardiovascular risk
• Diuretic therapy for fluid retention

Directions For Use

Take one tablet orally once daily with or without food, preferably at the same time each day.

Benefits

• Effective blood pressure control
• Reduces risk of stroke and heart attack
• Combines two complementary mechanisms
• Once-daily dosing for convenience
• Helps manage fluid retention
• Improves overall cardiovascular health

Side Effects

• Dizziness
• Lightheadedness
• Fatigue
• Headache
• Nausea
• Diarrhea
• Muscle cramps
• Low potassium levels
• Increased uric acid
• Cough (less common than ACE inhibitors)
• Orthostatic hypotension
• Kidney function impairment

Safety Measures

• Alcohol - Alcohol can further lower blood pressure and increase dizziness. Avoid or limit consumption.
• Pregnancy - Contraindicated in the second and third trimesters due to fetal toxicity.
• Breastfeeding - Not recommended during breastfeeding as components pass into breast milk.
• Liver - Use with caution in patients with liver impairment; monitor liver function.
• Kidney - Contraindicated in severe renal impairment; use with caution and monitor kidney function.
• Lung - Generally safe for use in patients with lung conditions, but monitor for electrolyte imbalances.

Disclaimer

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