TELMA 80MG TAB

About

Telma 80mg Tablet contains Telmisartan, an angiotensin II receptor blocker (ARB) primarily used for the treatment of essential hypertension. It works by selectively blocking the binding of angiotensin II to the AT1 receptor in various tissues, including vascular smooth muscle and the adrenal gland. This blockade prevents the vasoconstrictive and aldosterone-secreting effects of angiotensin II, leading to a significant reduction in blood pressure. Telmisartan is known for its long duration of action, allowing for convenient once-daily dosing, and its high lipophilicity contributes to its sustained effect.

Beyond blood pressure control, Telmisartan is also indicated for the reduction of cardiovascular morbidity and mortality in patients at high risk, such as those with established atherosclerotic cardiovascular disease or type 2 diabetes with target organ damage. Its efficacy in lowering blood pressure is comparable to other ARBs and ACE inhibitors, making it a valuable option in managing chronic hypertension and preventing associated cardiovascular events, particularly in patients who may not tolerate ACE inhibitors due to cough.

Uses

• Treatment of essential hypertension.
• Reduction of cardiovascular morbidity and mortality.
• Prevention of stroke and myocardial infarction.
• Management of diabetic nephropathy (off-label in some regions).

Directions For Use

Take one tablet orally once daily, with or without food, as directed by your physician.

Benefits

• Effective blood pressure reduction.
• Once-daily dosing for convenience.
• Reduces risk of cardiovascular events.
• Well-tolerated in many patients.
• May be suitable for patients intolerant to ACE inhibitors.
• Provides sustained blood pressure control.

Side Effects

• Dizziness
• Fatigue
• Headache
• Hypotension
• Hyperkalemia
• Back pain
• Diarrhea
• Nausea
• Upper respiratory tract infection
• Cough (less common than with ACE inhibitors)
• Angioedema (rare)
• Renal impairment

Safety Measures

• Alcohol - Alcohol may increase the blood pressure-lowering effect of Telmisartan, potentially leading to dizziness or lightheadedness. Use with caution.
• Pregnancy - Telmisartan is contraindicated during the second and third trimesters of pregnancy due to potential fetal harm, including renal dysfunction and death.
• Breastfeeding - Not recommended during breastfeeding as it may pass into breast milk and affect the infant. Consult a doctor.
• Liver - Use with caution in patients with severe hepatic impairment as Telmisartan is primarily eliminated via bile. Dose adjustment may be necessary.
• Kidney - Use with caution in patients with renal impairment; monitor kidney function regularly, especially in those with severe renal disease or renal artery stenosis.
• Lung - Generally safe for use in patients with lung conditions, as it does not typically cause respiratory side effects like cough associated with ACE inhibitors.

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