About
Tendia M combines Teneligliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, and Metformin, a biguanide, for the comprehensive management of type 2 diabetes mellitus in adults. Teneligliptin enhances glucose-dependent insulin secretion and suppresses glucagon release by inhibiting DPP-4, thereby increasing active incretin levels. Metformin primarily reduces hepatic glucose production, decreases intestinal glucose absorption, and improves peripheral insulin sensitivity. This dual-action medication addresses multiple pathophysiological defects of type 2 diabetes, leading to significant improvements in glycemic control. It is particularly beneficial for patients who have not achieved adequate blood sugar control with metformin monotherapy or who require the complementary effects of both drug classes.
Uses
- Management of type 2 diabetes mellitus.
- Improvement of glycemic control.
- Used as an add-on to diet and exercise.
- Initial therapy for type 2 diabetes.
Directions For Use
Take this medication orally, usually once or twice daily with meals, as directed by your doctor.
Benefits
- Effectively lowers blood sugar levels.
- Improves insulin sensitivity.
- Reduces hepatic glucose production.
- Low risk of hypoglycemia (when used alone).
- Convenient fixed-dose combination.
- Helps achieve target HbA1c levels.
Side Effects
- Nausea
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
- Fatigue
- Vomiting
- Metallic taste
- Lactic acidosis (rare, with Metformin)
- Pancreatitis (rare, with Teneligliptin)
- Joint pain
- Skin reactions
Safety Measures
- Alcohol - Avoid excessive alcohol consumption as it can increase the risk of lactic acidosis, especially with Metformin, and may cause hypoglycemia.
- Pregnancy - Generally not recommended during pregnancy. Consult a doctor; benefits must outweigh potential risks.
- Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk. Seek medical advice.
- Liver - Use with caution in patients with mild to moderate hepatic impairment. Contraindicated in severe liver disease due to increased risk of lactic acidosis.
- Kidney - Contraindicated in severe renal impairment (eGFR <30 mL/min/1.73m²). Dose adjustment required for moderate impairment.
- Lung - Use with caution in conditions causing hypoxia, which can increase the risk of lactic acidosis.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
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| Shop Location | Assam, India |
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