TERAVIR TAB 300MG 1X30

About

Tenofovir Disoproxil Fumarate (TDF) is a nucleotide reverse transcriptase inhibitor (NtRTI) used in the treatment of human immunodeficiency virus (HIV-1) infection and chronic hepatitis B virus (HBV) infection. TDF works by interfering with the reverse transcriptase enzyme, which is crucial for viral replication, thereby reducing viral load and improving immune function in HIV patients and liver health in HBV patients. It is often part of combination antiretroviral therapy for HIV and a first-line agent for chronic HBV, demonstrating significant efficacy in suppressing viral replication. Long-term use requires monitoring for potential renal toxicity, including Fanconi syndrome, and changes in bone mineral density, necessitating careful patient selection and ongoing clinical assessment to mitigate risks.

Uses

• Chronic hepatitis B virus (HBV) infection.
• Human immunodeficiency virus (HIV-1) infection.
• Pre-exposure prophylaxis (PrEP) for HIV.
• Post-exposure prophylaxis (PEP) for HIV.

Directions For Use

Take one tablet orally once daily with or without food.

Benefits

• Potent antiviral activity against HIV and HBV.
• Reduces viral load effectively.
• Improves immune function in HIV.
• Improves liver health in HBV.
• Convenient once-daily dosing.
• Part of highly effective combination therapies.

Side Effects

• Nausea
• Diarrhea
• Vomiting
• Abdominal pain
• Headache
• Dizziness
• Fatigue
• Renal impairment (nephrotoxicity)
• Decreased bone mineral density
• Lactic acidosis (rare)
• Fanconi syndrome (rare)
• Skin rash

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can worsen liver disease and potentially exacerbate kidney issues.
• Pregnancy - Generally considered safe; consult a specialist for risk-benefit assessment.
• Breastfeeding - Not recommended for HIV-positive mothers due to risk of HIV transmission; for HBV, consult a specialist.
• Liver - Use with caution in severe liver impairment; monitor liver function closely.
• Kidney - Dosage adjustment is required for patients with renal impairment; monitor renal function regularly.
• Lung - No specific contraindication; generally safe for use in patients with lung conditions.

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