TRANEXAREN TAB 10 S

About

Tranexaren, containing tranexamic acid, is a potent antifibrinolytic agent specifically designed to manage and prevent excessive bleeding by stabilizing blood clots. Its mechanism of action involves reversibly binding to plasminogen, a precursor to plasmin, thereby inhibiting the conversion of plasminogen to plasmin and subsequently preventing the degradation of fibrin. Fibrin is a critical protein that forms the meshwork of blood clots. By preserving this fibrin matrix, tranexamic acid effectively reduces the dissolution of clots, leading to decreased blood loss in various clinical scenarios. This includes conditions such as heavy menstrual bleeding, surgical procedures, and certain inherited bleeding disorders, making it a valuable tool in promoting hemostasis and improving patient outcomes.

Uses

• Treatment of heavy menstrual bleeding (menorrhagia).
• Prevention of bleeding in dental procedures for hemophiliacs.
• Management of epistaxis (nosebleeds).
• Reduction of blood loss during and after surgery.

Directions For Use

Take tablets orally as directed by your physician. Dosage and frequency depend on the condition being treated.

Benefits

• Effectively reduces blood loss.
• Promotes blood clot stability.
• Useful in various bleeding disorders.
• Reduces need for blood transfusions.
• Fast-acting in acute bleeding.
• Improves quality of life for menorrhagia.

Side Effects

• Nausea.
• Vomiting.
• Diarrhea.
• Abdominal pain.
• Headache.
• Dizziness.
• Allergic skin reactions.
• Visual disturbances (rare).
• Thromboembolic events (rare).
• Hypotension (with rapid IV infusion).
• Muscle cramps.
• Back pain.

Safety Measures

• Alcohol - No specific interaction with alcohol is generally noted, but excessive alcohol can impair clotting. It's advisable to consume alcohol in moderation.
• Pregnancy - Use only if clearly needed and the potential benefits outweigh the risks. Consult a doctor, as it crosses the placenta.
• Breastfeeding - Tranexamic acid is excreted into breast milk. Use with caution, and consult a doctor to weigh the benefits of breastfeeding against potential infant exposure.
• Liver - Use with caution in patients with liver disease, as it is primarily excreted unchanged in the urine. No specific dose adjustment is usually required.
• Kidney - Dose adjustment is necessary in patients with renal impairment due to reduced excretion. Contraindicated in severe renal failure.
• Lung - Use with caution in patients with a history of pulmonary embolism or other thromboembolic diseases, as it can increase the risk of clot formation.

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