VERTIN OD 24 TAB 7'S

About

Vertin OD (Once Daily) tablets contain Betahistine, a synthetic analog of histamine, primarily indicated for the symptomatic treatment of Meniere's disease and various forms of vertigo. The precise mechanism of action is complex but is believed to involve multiple pathways. Betahistine acts as a weak agonist at histamine H1 receptors and a potent antagonist at histamine H3 receptors. This dual action is thought to enhance microcirculation within the inner ear, particularly in the labyrinth, by causing vasodilation and increasing permeability.

Additionally, its H3-receptor antagonism may modulate neurotransmitter release in the central nervous system, influencing vestibular compensation. By improving blood flow and reducing endolymphatic pressure in the inner ear, Betahistine helps to alleviate the characteristic symptoms of Meniere's disease, including debilitating vertigo attacks, persistent tinnitus, and progressive hearing loss, thereby improving the patient's quality of life.

Uses

• Symptomatic treatment of Meniere's disease
• Relief of vertigo symptoms
• Reduction of tinnitus associated with inner ear disorders
• Improvement of hearing loss in Meniere's disease

Directions For Use

Take one tablet orally once daily, preferably with food, as directed by your physician. Do not crush or chew.

Benefits

• Reduces frequency and severity of vertigo attacks
• Alleviates tinnitus
• May improve hearing loss in Meniere's
• Once-daily dosing for convenience
• Targets inner ear microcirculation
• Generally well-tolerated

Side Effects

• Nausea
• Indigestion
• Headache
• Abdominal pain
• Bloating
• Vomiting
• Skin rash
• Itching
• Urticaria
• Drowsiness
• Diarrhea
• Heartburn

Safety Measures

• Alcohol - No specific interaction with alcohol is typically noted, but alcohol may worsen vertigo.
• Pregnancy - Consult a doctor; generally not recommended unless clearly needed.
• Breastfeeding - Not recommended; consult a healthcare professional as it may pass into breast milk.
• Liver - Use with caution in patients with liver impairment; consult a doctor.
• Kidney - Use with caution in patients with kidney impairment; consult a doctor.
• Lung - Use with caution in patients with bronchial asthma due to its histamine-like effects.

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