ALFALOG TAB

About

Alfacalcidol is a synthetic vitamin D analog, specifically a prodrug that undergoes hydroxylation in the liver to become calcitriol, the active form of vitamin D. This active metabolite plays a crucial role in regulating calcium and phosphate homeostasis within the body. It is particularly vital for patients with compromised renal function, as their kidneys may be unable to perform the necessary 1-alpha-hydroxylation of native vitamin D. By providing a readily convertible form, Alfacalcidol helps to normalize serum calcium levels, enhance intestinal absorption of dietary calcium, and promote proper bone mineralization. This action is essential in managing various metabolic bone diseases, including renal osteodystrophy, hypoparathyroidism, and certain forms of rickets and osteomalacia, thereby preventing complications associated with mineral imbalances and supporting skeletal health.

Uses

• Renal osteodystrophy
• Hypoparathyroidism
• Osteoporosis (in certain cases)
• Rickets and osteomalacia

Directions For Use

Take orally as directed by your physician, usually once daily.

Benefits

• Corrects hypocalcemia
• Improves bone mineral density
• Reduces risk of fractures
• Supports parathyroid function
• Enhances intestinal calcium absorption
• Manages renal bone disease

Side Effects

• Hypercalcemia
• Nausea
• Vomiting
• Constipation
• Abdominal pain
• Headache
• Weakness
• Fatigue
• Polyuria
• Polydipsia
• Anorexia
• Metallic taste

Safety Measures

• Alcohol - No specific interaction, but excessive alcohol can impair bone health.
• Pregnancy - Use with caution; high doses may be teratogenic. Consult a doctor.
• Breastfeeding - Excreted in breast milk; monitor infant for hypercalcemia. Consult a doctor.
• Liver - Metabolized in the liver; use with caution in severe liver impairment.
• Kidney - Primarily used in renal impairment, but monitor calcium and phosphate levels closely.
• Lung - No direct impact on lung function.

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