About
Alsartan 50mg Tablet contains Valsartan, an angiotensin II receptor blocker (ARB) used primarily for the treatment of hypertension, heart failure, and to improve survival after a myocardial infarction. Valsartan works by selectively blocking the AT1 receptor, preventing angiotensin II from binding and exerting its vasoconstrictive and aldosterone-stimulating effects. This leads to relaxation of blood vessels, a decrease in blood pressure, and a reduction in the workload on the heart. Its action helps to reduce peripheral vascular resistance without affecting heart rate.
The medication is effective in managing high blood pressure, which is a major risk factor for cardiovascular diseases. In patients with heart failure, Valsartan helps to improve symptoms and reduce hospitalizations by counteracting the harmful effects of angiotensin II on the heart and blood vessels. For post-myocardial infarction patients, it helps to improve outcomes by preventing cardiac remodeling. Consistent adherence to the prescribed dosage is essential for achieving therapeutic benefits and minimizing cardiovascular risks.
Uses
- Treatment of essential hypertension
- Management of heart failure
- Improvement of survival after myocardial infarction
- Reduction of cardiovascular mortality and morbidity
Directions For Use
Take this medicine orally as directed by your physician, usually once or twice daily. It can be taken with or without food.
Benefits
- Effectively lowers high blood pressure
- Improves symptoms and outcomes in heart failure patients
- Reduces mortality after a heart attack
- Provides sustained blood pressure control
- Generally well-tolerated with a low incidence of cough
- Helps protect target organs from hypertension-related damage
Side Effects
- Dizziness
- Headache
- Fatigue
- Nausea
- Diarrhea
- Abdominal pain
- Hyperkalemia (high potassium levels)
- Renal impairment
- Hypotension (low blood pressure)
- Cough (less common than with ACE inhibitors)
- Back pain
- Angioedema (rare, severe allergic reaction)
Safety Measures
- Alcohol - Alcohol may enhance the hypotensive effects of Valsartan, increasing the risk of dizziness or fainting. It is advisable to limit alcohol intake.
- Pregnancy - Valsartan is contraindicated during pregnancy, especially in the second and third trimesters, due to significant risks of fetal injury and death.
- Breastfeeding - It is not recommended during breastfeeding as Valsartan may be excreted in breast milk and could potentially harm the nursing infant. Consult your doctor.
- Liver - Use with caution in patients with mild to moderate hepatic impairment. Dose adjustment may be necessary. Not recommended in severe hepatic impairment.
- Kidney - Monitor renal function closely in patients with kidney impairment. Dose adjustment may be required, and it is contraindicated in severe renal artery stenosis.
- Lung - Valsartan is generally safe for patients with lung conditions, as it does not typically induce the dry cough commonly associated with ACE inhibitors.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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