AMLONG 5 MG TAB

About

Amlong 5 MG contains Amlodipine, a long-acting dihydropyridine calcium channel blocker, widely used for the management of essential hypertension and various forms of angina pectoris. Amlodipine exerts its therapeutic effects by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle cells. This leads to a relaxation of the smooth muscles in the walls of peripheral arteries, resulting in vasodilation and a significant reduction in peripheral vascular resistance. Consequently, blood pressure is lowered, and the workload on the heart is decreased.

In patients with angina, this action increases myocardial oxygen supply by dilating coronary arteries and reduces oxygen demand by lowering afterload. Its prolonged duration of action allows for convenient once-daily dosing, providing sustained blood pressure control and effective symptomatic relief for angina, thereby improving patient outcomes and reducing cardiovascular risk.

Uses

• Treatment of essential hypertension.
• Management of chronic stable angina.
• Treatment of vasospastic angina (Prinzmetal's angina).
• To reduce the risk of cardiovascular events in hypertensive patients.

Directions For Use

Take once daily, preferably at the same time each day, with or without food.

Benefits

• Effective in lowering high blood pressure.
• Reduces frequency and severity of angina attacks.
• Improves exercise tolerance in angina patients.
• Provides sustained 24-hour blood pressure control.
• Well-tolerated in many patients.
• Helps prevent cardiovascular complications.

Side Effects

• Dizziness
• Headache
• Fatigue
• Swelling in ankles/feet (edema)
• Nausea
• Flushing
• Palpitations
• Abdominal pain
• Somnolence
• Muscle cramps
• Rash
• Visual disturbances

Safety Measures

• Alcohol - Avoid or limit alcohol as it can increase the blood pressure-lowering effect and enhance dizziness.
• Pregnancy - Use with caution during pregnancy only if clearly needed, as data on human pregnancy is limited.
• Breastfeeding - Amlodipine is excreted in breast milk; use with caution, and monitor the infant for adverse effects.
• Liver - Use with caution in patients with liver impairment, as amlodipine is extensively metabolized in the liver, and dose adjustment may be necessary.
• Kidney - Generally safe for use in patients with kidney conditions, as it is not significantly renally excreted, but caution in severe cases.
• Lung - Generally safe for use in patients with lung conditions, as it does not directly affect respiratory function.

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