Anasted 1mg Tablet

About

Anastrozole, a potent and highly selective non-steroidal aromatase inhibitor, plays a critical role in the management of hormone receptor-positive breast cancer in postmenopausal women. The enzyme aromatase is responsible for the conversion of adrenal androgens into estrogens in peripheral tissues, which is the primary source of estrogen in postmenopausal women. By effectively blocking this enzyme, anastrozole significantly lowers circulating estrogen levels. This reduction in estrogen deprives hormone-sensitive breast cancer cells of the growth stimulus they require, thereby inhibiting tumor progression.

It is widely used as an adjuvant therapy for early breast cancer and as a first-line treatment for advanced breast cancer, including cases that have progressed after tamoxifen therapy. Its targeted action helps to improve patient outcomes by reducing the risk of recurrence and extending disease-free survival in appropriate patient populations.

Uses

• Adjuvant treatment of early hormone receptor-positive breast cancer in postmenopausal women.
• First-line treatment of hormone receptor-positive advanced breast cancer in postmenopausal women.
• Treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy.
• Extended adjuvant treatment for postmenopausal women with early breast cancer.

Directions For Use

Take one tablet orally once daily, at the same time each day. Adhere strictly to your doctor's instructions.

Benefits

• Effectively lowers estrogen levels, inhibiting cancer growth.
• Reduces the risk of breast cancer recurrence.
• Improves survival rates in early breast cancer.
• Provides a valuable treatment option for advanced disease.
• Well-established efficacy in postmenopausal women.
• Simple once-daily oral dosing regimen.

Side Effects

• Hot flashes
• Joint pain
• Nausea
• Fatigue
• Headache
• Bone pain
• Vaginal dryness
• Hair thinning
• Osteoporosis
• Increased cholesterol levels
• Peripheral edema
• Rash

Safety Measures

• Alcohol - Moderate alcohol consumption is generally acceptable, but excessive intake may exacerbate certain side effects like hot flashes.
• Pregnancy - Anastrozole is contraindicated in pregnant women due as it can cause fetal harm. Effective contraception is required for premenopausal women.
• Breastfeeding - It is not known if anastrozole is excreted in human milk. Due to the potential for serious adverse effects in infants, breastfeeding is contraindicated.
• Liver - Use with caution in patients with moderate to severe hepatic impairment. Close monitoring of liver function may be necessary.
• Kidney - No dose adjustment is typically required for mild to moderate renal impairment. Use with caution in severe renal impairment.
• Lung - Generally considered safe for use in patients with lung conditions, as it does not directly affect respiratory function.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.