About
Angizaar 50 mg tablets contain Losartan, an angiotensin II receptor blocker (ARB). This medication works by selectively blocking the binding of angiotensin II to the AT1 receptor, which is responsible for the vasoconstrictive and aldosterone-secreting effects of angiotensin II. By inhibiting these actions, Losartan causes vasodilation, reduces blood pressure, and decreases the workload on the heart. It is widely used in the management of hypertension and heart failure, and also offers renal protection in patients with type 2 diabetes and nephropathy. Its mechanism helps to prevent cardiovascular events and improve overall cardiac function.
Losartan is generally well-tolerated and provides a sustained reduction in blood pressure, making it an effective choice for long-term management of cardiovascular conditions. It is often preferred over ACE inhibitors in patients who develop a cough with the latter, as ARBs typically do not cause this side effect. Regular monitoring of blood pressure and kidney function is recommended during treatment.
Uses
- Treatment of essential hypertension.
- Management of heart failure.
- Reduction of the risk of stroke in patients with hypertension and left ventricular hypertrophy.
- Renal protection in patients with type 2 diabetes and nephropathy.
Directions For Use
Take one tablet orally once daily, with or without food, as directed by your physician.
Benefits
- Effectively lowers high blood pressure.
- Reduces the risk of cardiovascular events.
- Provides kidney protection in diabetic patients.
- Well-tolerated with a low incidence of cough.
- Helps manage symptoms of heart failure.
- Offers sustained 24-hour blood pressure control.
Side Effects
- Dizziness
- Fatigue
- Hyperkalemia
- Hypotension
- Nausea
- Diarrhea
- Back pain
- Muscle cramps
- Upper respiratory infection
- Sinusitis
- Angioedema (rare)
- Renal impairment (especially in susceptible patients)
Safety Measures
- Alcohol - Alcohol may enhance the hypotensive effect of Losartan, leading to increased dizziness or lightheadedness. It is advisable to limit alcohol intake.
- Pregnancy - Losartan is contraindicated during pregnancy, especially in the second and third trimesters, due to potential fetal harm and toxicity.
- Breastfeeding - Not recommended during breastfeeding as Losartan may pass into breast milk and could harm the infant. Consult your doctor.
- Liver - Use with caution in patients with liver impairment. Dose adjustment may be necessary, and liver function should be monitored.
- Kidney - Use with caution in patients with renal impairment. Monitor kidney function regularly, and dose adjustment may be required.
- Lung - Generally considered safe for patients with lung conditions, as it is less likely to cause cough compared to ACE inhibitors.
Disclaimer
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