ARBITEL CT 80 TAB

About

ARBITEL CT 80 TAB combines Telmisartan, an angiotensin II receptor blocker (ARB), with Chlorthalidone, a long-acting thiazide-like diuretic. Telmisartan works by selectively inhibiting the binding of angiotensin II to the AT1 receptor, leading to vasodilation and reduced aldosterone secretion. Chlorthalidone increases the excretion of sodium and water by inhibiting sodium reabsorption in the cortical diluting segment of the nephron, thereby reducing plasma volume. This combination provides a potent antihypertensive effect by reducing both peripheral vascular resistance and plasma volume. It is particularly effective for managing essential hypertension, especially in patients who require more robust blood pressure control or have not achieved target blood pressure with monotherapy. The synergistic action helps to lower blood pressure more effectively and reduce the risk of cardiovascular events.

Uses

• Treatment of essential hypertension.
• Reduction of cardiovascular morbidity and mortality.
• Management of hypertension in patients requiring combination therapy.
• Prevention of stroke and myocardial infarction in high-risk individuals.

Directions For Use

Take orally once daily, with or without food, as prescribed by your healthcare provider.

Benefits

• Potent and sustained blood pressure reduction.
• Reduces the risk of major cardiovascular events.
• Offers superior blood pressure control compared to single agents.
• Convenient once-daily dosing regimen.
• May provide additional benefits in patients with fluid retention.
• Generally well-tolerated for long-term management.

Side Effects

• Dizziness or lightheadedness
• Fatigue
• Headache
• Nausea
• Diarrhea
• Muscle cramps
• Hypotension
• Hypokalemia
• Hyperuricemia
• Hyperglycemia
• Rash or photosensitivity
• Electrolyte imbalances

Safety Measures

• Alcohol - Limit or avoid alcohol as it can intensify the blood pressure-lowering effect, increasing the risk of dizziness and fainting.
• Pregnancy - Contraindicated during pregnancy, especially in the second and third trimesters, due to significant risk of fetal renal dysfunction and mortality.
• Breastfeeding - Not recommended during breastfeeding as both active ingredients can pass into breast milk and may cause adverse effects in the nursing infant.
• Liver - Use with caution in patients with severe hepatic impairment; dose adjustment may be necessary due to altered drug metabolism and excretion.
• Kidney - Use with caution in patients with severe renal impairment; close monitoring of kidney function and electrolytes is essential due to potential for worsening renal function.
• Lung - Generally considered safe for patients with lung conditions; however, monitor for any unusual respiratory symptoms, though not a common side effect.

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