Bd-Letro 2.5mg Tablet

About

Bd-Letro 2.5mg Tablet is a potent third-generation aromatase inhibitor, specifically indicated for the treatment of hormone-receptor-positive breast cancer in postmenopausal women. Its primary mechanism involves selectively and potently inhibiting the enzyme aromatase, which is responsible for the peripheral conversion of adrenal androgens into estrogens. By significantly reducing circulating estrogen levels, this medication effectively deprives estrogen-dependent breast cancer cells of the growth stimulus they require, thereby inhibiting tumor proliferation and promoting regression. It plays a critical role in both adjuvant therapy following surgery to reduce recurrence risk and as a first-line or subsequent treatment for advanced or metastatic disease, offering a targeted endocrine therapy approach to improve long-term survival and disease control in appropriate patient populations.

Uses

• Adjuvant treatment of early breast cancer in postmenopausal women.
• First-line treatment of advanced breast cancer in postmenopausal women.
• Extended adjuvant treatment for early breast cancer.
• Treatment of advanced breast cancer after anti-estrogen therapy.

Directions For Use

Take one tablet orally once daily, with or without food, as prescribed by your doctor.

Benefits

• Effectively lowers estrogen levels.
• Inhibits growth of hormone-sensitive breast cancer.
• Reduces risk of cancer recurrence.
• Improves disease-free survival.
• Convenient oral administration.
• Well-established efficacy in postmenopausal women.

Side Effects

• Hot flashes
• Joint pain (arthralgia)
• Fatigue
• Nausea
• Headache
• Bone thinning (osteoporosis)
• Hair thinning
• Weight gain
• Dizziness
• High cholesterol
• Vaginal dryness
• Peripheral edema

Safety Measures

• Alcohol - Moderate alcohol consumption is generally acceptable, but excessive intake may increase the risk of bone loss.
• Pregnancy - Contraindicated in pregnancy due to potential for fetal harm. Not for use in premenopausal women unless effective contraception is used.
• Breastfeeding - Not recommended during breastfeeding as it may pass into breast milk and harm the infant.
• Liver - Use with caution in patients with severe hepatic impairment; dose adjustments may be necessary.
• Kidney - Generally safe in patients with mild to moderate renal impairment; no dose adjustment typically required.
• Lung - No specific lung-related precautions, but monitor for any new or worsening respiratory symptoms.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.