Bdron 500mg Tablet

About

Bdron 500mg Tablet is an anti-arrhythmic medication primarily used to treat and prevent various types of severe ventricular and supraventricular arrhythmias. It belongs to the Class III anti-arrhythmic agents, working by prolonging the cardiac action potential and refractory period in myocardial tissue. This effect is achieved through the blockade of potassium channels, which delays repolarization. Additionally, it exhibits non-competitive alpha- and beta-adrenergic blocking activity, and some sodium and calcium channel blocking properties, contributing to its broad anti-arrhythmic spectrum.

The complex electrophysiological effects of Bdron 500mg Tablet help to stabilize abnormal heart rhythms, restoring a more regular and effective heartbeat. Due to its extensive tissue distribution and long half-life, it accumulates in various organs, which contributes to its prolonged therapeutic effects but also to its potential for significant systemic side effects. Its use is typically reserved for life-threatening arrhythmias or when other anti-arrhythmic agents are ineffective or contraindicated.

Uses

• Treatment of life-threatening recurrent ventricular fibrillation.
• Management of recurrent hemodynamically unstable ventricular tachycardia.
• Prevention of recurrent atrial fibrillation.
• Treatment of other severe supraventricular tachyarrhythmias.

Directions For Use

Take orally as directed by your cardiologist, usually with food to improve absorption and reduce gastrointestinal upset. Do not stop abruptly.

Benefits

• Highly effective in controlling severe arrhythmias.
• Broad spectrum anti-arrhythmic activity.
• Can be used for both ventricular and supraventricular arrhythmias.
• Prolongs cardiac action potential.
• Reduces risk of sudden cardiac death in high-risk patients.
• Maintains sinus rhythm in atrial fibrillation.

Side Effects

• Nausea
• Vomiting
• Constipation
• Tremor
• Dizziness
• Fatigue
• Photosensitivity
• Corneal microdeposits
• Thyroid dysfunction (hypo/hyperthyroidism)
• Pulmonary toxicity (fibrosis)
• Liver enzyme elevation
• Bradycardia

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can exacerbate liver toxicity and potentially interact with the medication's effects on the heart.
• Pregnancy - Contraindicated during pregnancy due to significant risk of fetal harm, including thyroid abnormalities; use only if life-threatening and no safer alternative exists.
• Breastfeeding - Not recommended during breastfeeding as it is excreted into breast milk and can cause serious adverse effects in the infant, including thyroid dysfunction.
• Liver - Use with extreme caution in patients with liver disease; regular monitoring of liver function tests is essential due to risk of hepatotoxicity.
• Kidney - Generally safe for use in patients with kidney conditions; no dose adjustment typically required, but monitor for overall systemic effects.
• Lung - Contraindicated or used with extreme caution in patients with pre-existing lung disease due to the significant risk of severe and potentially fatal pulmonary toxicity (e.g., pulmonary fibrosis).

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