Bevarest 100mg Injection

About

Bevarest is a recombinant humanized monoclonal antibody that selectively binds to and neutralizes vascular endothelial growth factor (VEGF), a key mediator of angiogenesis. By inhibiting VEGF, this medication prevents the formation of new blood vessels that tumors need to grow and spread, thereby starving the tumor of essential nutrients and oxygen. It is often used in combination with chemotherapy to enhance its efficacy and improve patient outcomes. Its mechanism of action targets the tumor microenvironment rather than directly cytotoxic effects on cancer cells, making it a crucial component in modern oncology regimens for various advanced malignancies. The therapeutic goal is to slow disease progression, reduce tumor burden, and ultimately improve both progression-free survival and overall survival in patients battling specific types of cancer. This targeted approach minimizes damage to healthy cells compared to traditional chemotherapy, offering a more precise treatment option.

Uses

• Treatment of metastatic colorectal cancer.
• Management of non-small cell lung cancer.
• Therapy for metastatic renal cell carcinoma.
• Treatment of recurrent glioblastoma.

Directions For Use

Administered intravenously by a healthcare professional. Dosage and frequency are determined by the patient's condition and treatment regimen.

Benefits

• Inhibits tumor growth and metastasis.
• Extends progression-free survival.
• Improves overall survival in certain cancers.
• Can be combined with various chemotherapies.
• Targets a specific pathway crucial for tumor angiogenesis.
• Offers a targeted approach to cancer therapy.

Side Effects

• Hypertension
• Proteinuria
• Bleeding events
• Thromboembolic events
• Gastrointestinal perforation
• Wound healing complications
• Fatigue
• Headache
• Diarrhea
• Nausea
• Taste alteration
• Infusion-related reactions

Safety Measures

• Alcohol - No direct interaction with alcohol is typically noted, but alcohol consumption should be discussed with a doctor, especially during cancer treatment.
• Pregnancy - Contraindicated due to potential for fetal harm, including birth defects and miscarriage. Effective contraception is required during treatment and for several months post-treatment.
• Breastfeeding - Not recommended as the drug may pass into breast milk and harm the infant. Discontinue breastfeeding during treatment and for a period after the last dose.
• Liver - Use with caution in patients with pre-existing liver conditions. Liver function should be monitored regularly during treatment.
• Kidney - Use with caution in patients with pre-existing kidney conditions. Renal function should be monitored, especially due to potential for proteinuria.
• Lung - Use with caution in patients with a history of pulmonary hemorrhage or other lung conditions. Monitor for respiratory symptoms.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.