Celnalid 5mg Capsule

About

Celnalid Capsules, available in 5mg and 10mg strengths, are an advanced immunomodulatory drug primarily used in the management of specific hematologic malignancies. This medication works by modulating the immune system, directly inhibiting the proliferation of certain cancer cells, and interfering with the formation of new blood vessels that support tumor growth. Its multifaceted mechanism of action makes it a valuable therapeutic option for conditions such as multiple myeloma, where it can be used alone or in combination with other agents to enhance efficacy. Celnalid also possesses anti-inflammatory properties, contributing to its therapeutic benefits in certain myelodysplastic syndromes. Due to its potent effects and potential for serious adverse reactions, including a significant risk of birth defects, treatment with Celnalid requires careful patient selection and ongoing monitoring by a specialist, adhering strictly to prescribed risk evaluation and mitigation strategies.

Uses

• Multiple myeloma
• Myelodysplastic syndromes (MDS)
• Mantle cell lymphoma (MCL)
• Follicular lymphoma (FL)

Directions For Use

Take orally with a full glass of water, at the same time each day, with or without food. Do not crush, chew, or open the capsule.

Benefits

• Targets specific cancer cells effectively
• Enhances the body's immune response
• Inhibits tumor angiogenesis
• Improves survival rates in certain cancers
• Reduces disease progression
• Offers a targeted approach to cancer therapy

Side Effects

• Fatigue
• Diarrhea
• Constipation
• Nausea
• Rash
• Peripheral neuropathy
• Thrombocytopenia
• Neutropenia
• Deep vein thrombosis
• Pulmonary embolism
• Muscle cramps
• Dizziness

Safety Measures

• Alcohol - Alcohol consumption should be avoided or minimized during treatment, as it may worsen side effects like fatigue or dizziness and could potentially interact with the medication.
• Pregnancy - ABSOLUTELY CONTRAINDICATED. Celnalid is a known human teratogen causing severe birth defects. Strict adherence to risk management programs, including contraception, is mandatory for all patients.
• Breastfeeding - Due to the potential for serious adverse reactions in a breastfed infant, breastfeeding is not recommended during treatment with Celnalid.
• Liver - Use with caution in patients with hepatic impairment. Close monitoring of liver function tests is essential, and dose adjustments may be required.
• Kidney - Renal impairment necessitates dose adjustments, as Celnalid is primarily eliminated via the kidneys. Regular monitoring of kidney function is crucial.
• Lung - Patients should be monitored for signs of interstitial lung disease or pulmonary hypertension, which are rare but serious potential side effects.

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