Ciclib 75mg Capsule

About

Ciclib 75mg Capsule contains a cyclin-dependent kinase (CDK) 4/6 inhibitor, a class of targeted therapy used primarily in the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast cancer. This medication works by selectively inhibiting CDK4 and CDK6, enzymes that play a crucial role in regulating cell cycle progression from the G1 to S phase. By blocking these kinases, Ciclib prevents cancer cells from dividing and proliferating, thereby slowing tumor growth and progression.

It is typically used in combination with endocrine therapy, enhancing the effectiveness of hormonal treatments by overcoming resistance mechanisms. The oral administration of Ciclib offers convenience for patients, but close monitoring for potential side effects, particularly myelosuppression (neutropenia) and gastrointestinal issues like diarrhea, is essential. Regular blood tests are required to manage and mitigate these adverse events, ensuring patient safety and optimal treatment outcomes.

Uses

• HR+/HER2- advanced or metastatic breast cancer
• In combination with aromatase inhibitors
• In combination with fulvestrant
• As monotherapy in specific cases

Directions For Use

Take this medicine orally with or without food, as directed by your oncologist.

Swallow the capsule whole; do not chew, crush, or open it.

Benefits

• Improves progression-free survival in breast cancer
• Offers targeted therapy for specific cancer types
• Oral administration provides convenience
• Effective in combination with endocrine therapy
• Helps overcome resistance to hormonal treatments
• Can delay disease progression in advanced settings

Side Effects

• Diarrhea
• Neutropenia (low white blood cell count)
• Fatigue and weakness
• Nausea and vomiting
• Abdominal pain
• Infections
• Anemia (low red blood cell count)
• Thrombocytopenia (low platelet count)
• Elevated liver enzymes
• Stomatitis (mouth sores)
• Hair thinning (alopecia)
• Venous thromboembolism (blood clots)

Safety Measures

• Alcohol - Exercise caution with alcohol consumption. It may exacerbate certain side effects like diarrhea or liver toxicity. Consult your doctor.
• Pregnancy - Ciclib 75mg Capsule is contraindicated in pregnancy due to potential fetal harm. Women of childbearing potential must use effective contraception during and for at least 3 weeks after treatment.
• Breastfeeding - Breastfeeding is not recommended during treatment with Ciclib 75mg Capsule and for at least 3 weeks after the last dose due to potential harm to the infant.
• Liver - Use with caution in patients with hepatic impairment. Dose adjustments may be necessary, and liver function should be monitored regularly.
• Kidney - Use with caution in patients with renal impairment. Dose adjustments may be required, and kidney function should be monitored.
• Lung - Rare cases of interstitial lung disease (ILD) or pneumonitis have been reported. Monitor for new or worsening respiratory symptoms.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.