About
Cytotam 10mg Tablet, containing Tamoxifen, is a selective estrogen receptor modulator (SERM) primarily used in the treatment and prevention of estrogen receptor-positive breast cancer. It works by binding to estrogen receptors in breast cancer cells, thereby blocking estrogen's ability to stimulate cancer cell growth. This mechanism makes it effective in both adjuvant settings, following primary treatment, and in metastatic disease, where it helps to control tumor progression.
Tamoxifen is also utilized in reducing the risk of invasive breast cancer in women at high risk and for ductal carcinoma in situ (DCIS) after surgery and radiation. Its long-term use requires careful monitoring due to potential side effects, including an increased risk of endometrial cancer and thromboembolic events. Patients are typically advised to take this medication for several years, as prescribed by their oncologist, to maximize its therapeutic benefits.
Uses
- Treatment of estrogen receptor-positive breast cancer in women and men.
- Adjuvant therapy for early-stage breast cancer.
- Reduction in the incidence of invasive breast cancer in high-risk women.
- Treatment of ductal carcinoma in situ (DCIS) after surgery and radiation.
Directions For Use
Take this medicine orally as directed by your physician, usually once or twice daily. Swallow the tablet whole with water.
Benefits
- Reduces recurrence risk in hormone-sensitive breast cancer.
- Effective in both early and advanced breast cancer.
- Can prevent breast cancer in high-risk individuals.
- Oral administration offers convenience.
- Improves overall survival rates in specific patient populations.
- Well-established efficacy profile over decades of use.
Side Effects
- Hot flashes
- Nausea
- Vaginal discharge
- Irregular periods
- Fluid retention
- Fatigue
- Headache
- Skin rash
- Hair thinning
- Thromboembolic events (rare but serious)
- Endometrial cancer (rare but serious)
- Cataracts
Safety Measures
- Alcohol - Alcohol consumption should be limited or avoided as it may increase the risk of liver side effects and potentially interact with tamoxifen metabolism.
- Pregnancy - Tamoxifen is contraindicated during pregnancy due to potential harm to the fetus. Effective contraception must be used during treatment and for several months after.
- Breastfeeding - Breastfeeding is not recommended during tamoxifen therapy as the drug may pass into breast milk and harm the infant.
- Liver - Use with caution in patients with pre-existing liver conditions. Liver function should be monitored regularly during treatment.
- Kidney - Generally considered safe for use in patients with kidney conditions, but caution is advised in severe renal impairment.
- Lung - No specific contraindications or major concerns regarding lung conditions, but general patient health should be considered.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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