Etbmed 100mg Tablet

About

Etbmed 100mg Tablet contains Ethambutol, a bacteriostatic antimycobacterial agent primarily used in the treatment of tuberculosis. It works by inhibiting arabinosyl transferases, enzymes essential for the biosynthesis of the mycobacterial cell wall. This disruption impairs the formation of the arabinogalactan layer, leading to increased cell wall permeability and inhibition of bacterial replication. Ethambutol is always administered as part of a multi-drug regimen to prevent the development of drug resistance and to achieve optimal therapeutic outcomes against Mycobacterium tuberculosis.

Its selective action against mycobacteria makes it a crucial component in both initial and retreatment phases of tuberculosis therapy. While generally well-tolerated, its most significant adverse effect is dose-related optic neuritis, necessitating regular ophthalmological monitoring. The drug is well-absorbed orally and excreted primarily by the kidneys, requiring dose adjustments in patients with renal impairment. Its role is vital in combating the global burden of tuberculosis.

Uses

• Pulmonary tuberculosis
• Extrapulmonary tuberculosis
• Mycobacterium avium complex (MAC) infections
• Drug-resistant tuberculosis regimens

Directions For Use

Take this tablet orally once daily, preferably with food to minimize gastrointestinal upset. Follow your doctor's prescribed dosage and duration.

Benefits

• Essential component of multi-drug TB regimens
• Effective against Mycobacterium tuberculosis
• Helps prevent the development of drug resistance
• Reduces bacterial load in infected tissues
• Available in convenient oral form
• Well-absorbed from the gastrointestinal tract

Side Effects

• Optic neuritis (vision loss, red-green color blindness)
• Peripheral neuropathy
• Headache
• Dizziness
• Nausea and vomiting
• Abdominal pain
• Rash
• Fever
• Joint pain (arthralgia)
• Hyperuricemia (gout-like symptoms)
• Anaphylaxis (rare)

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it may exacerbate neurological side effects.
• Pregnancy - Generally considered safe for use during pregnancy, but use with caution and only if clearly needed.
• Breastfeeding - Excreted in breast milk; generally considered compatible but monitor infant for potential side effects.
• Liver - Use with caution; monitor liver function, though it is not primarily hepatotoxic.
• Kidney - Dosage adjustment is crucial in patients with renal impairment due to renal excretion.
• Lung - No specific lung-related contraindications beyond its use for lung infections.

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