Femistra 1mg Tablet

About

Femistra 1mg Tablet contains Anastrozole, an aromatase inhibitor primarily used in postmenopausal women for the treatment of hormone receptor-positive early or advanced breast cancer. It works by significantly reducing the amount of estrogen produced in the body, which is a key hormone that can stimulate the growth of certain types of breast cancer cells. By inhibiting the aromatase enzyme, Anastrozole effectively blocks the conversion of androgens into estrogens in peripheral tissues, thereby lowering systemic estrogen levels. This action helps to slow or stop the growth of estrogen-sensitive tumors.

This medication is often prescribed as an adjuvant therapy following surgery or other treatments, or as a first-line treatment for advanced disease. Its selective mechanism of action makes it a valuable option in endocrine therapy for breast cancer, offering a targeted approach to managing hormone-dependent malignancies.

Uses

• Adjuvant treatment of early breast cancer in postmenopausal women.
• First-line treatment of hormone receptor-positive advanced breast cancer in postmenopausal women.
• Treatment of advanced breast cancer in postmenopausal women with disease progression following tamoxifen therapy.
• Extended adjuvant treatment of early breast cancer in postmenopausal women who have received 2 to 3 years of adjuvant tamoxifen.

Directions For Use

Take one tablet orally once daily, with or without food, as directed by your physician.

Benefits

• Significantly reduces estrogen levels in postmenopausal women.
• Inhibits the growth of hormone receptor-positive breast cancer cells.
• Improves disease-free survival in early breast cancer.
• Effective as first-line and second-line therapy for advanced breast cancer.
• Oral administration offers convenience for long-term treatment.
• Well-established efficacy in endocrine therapy for breast cancer.

Side Effects

• Hot flashes
• Joint pain (arthralgia)
• Nausea
• Headache
• Fatigue
• Bone pain
• Vaginal dryness
• Hair thinning
• Rash
• Vomiting
• Diarrhea
• Dizziness

Safety Measures

• Alcohol - Moderate alcohol consumption is generally not contraindicated, but excessive intake may exacerbate some side effects like liver issues or dizziness.
• Pregnancy - Contraindicated in pregnant women as it can cause fetal harm. Effective contraception must be used by premenopausal women if there is a possibility of pregnancy.
• Breastfeeding - Not recommended during breastfeeding due to potential harm to the infant and suppression of milk production.
• Liver - Use with caution in patients with moderate to severe liver impairment; dose adjustment may be necessary. Monitor liver function regularly.
• Kidney - No dose adjustment is typically required for mild to moderate renal impairment. Use with caution in severe impairment, though data is limited.
• Lung - Generally no specific lung-related precautions, but monitor for any new or worsening respiratory symptoms.

Disclaimer

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