About
GLIZID MV is a triple combination medication designed for the comprehensive management of type 2 diabetes mellitus. It typically contains Gliclazide, a sulfonylurea; Metformin, a biguanide; and Voglibose, an alpha-glucosidase inhibitor. Gliclazide stimulates the pancreas to release more insulin, helping to lower blood glucose. Metformin reduces glucose production by the liver and improves insulin sensitivity in peripheral tissues, while also decreasing intestinal glucose absorption. Voglibose works by delaying the digestion and absorption of carbohydrates from the gastrointestinal tract, thereby reducing post-meal blood sugar spikes.
This multi-faceted approach targets different aspects of glucose metabolism, providing robust control over both fasting and post-prandial blood sugar levels. GLIZID MV is prescribed when diet, exercise, and dual therapy are insufficient to achieve optimal glycemic targets. It aims to improve overall glycemic control, reduce the risk of diabetes-related complications, and offer a convenient treatment option for patients requiring intensive management.
Uses
- Management of type 2 diabetes mellitus.
- To achieve comprehensive glycemic control.
- Used as an adjunct to diet and exercise.
- When dual therapy is inadequate.
Directions For Use
Take this medicine orally with food, as directed by your physician. Swallow the tablet whole with a glass of water.
Benefits
- Comprehensive blood sugar control.
- Targets fasting and post-meal glucose.
- Reduces risk of diabetes complications.
- Improves insulin sensitivity.
- Convenient triple therapy.
- Helps manage weight (Metformin component).
Side Effects
- Hypoglycemia (low blood sugar)
- Nausea
- Diarrhea
- Abdominal pain
- Flatulence
- Headache
- Dizziness
- Metallic taste
- Lactic acidosis (rare but serious)
- Vitamin B12 deficiency
- Skin rash
- Constipation
Safety Measures
- Alcohol - Avoid excessive alcohol consumption as it can increase the risk of hypoglycemia (Gliclazide) and lactic acidosis (Metformin).
- Pregnancy - Generally not recommended during pregnancy. Consult your doctor, as insulin therapy is often preferred for gestational diabetes.
- Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk and affect the infant. Seek medical advice.
- Liver - Use with caution in patients with liver impairment, as it may increase the risk of lactic acidosis and affect drug metabolism.
- Kidney - Contraindicated in severe kidney impairment due to increased risk of lactic acidosis (Metformin) and accumulation of Gliclazide. Dose adjustment may be needed for moderate impairment.
- Lung - Generally safe for use in patients with stable lung conditions. However, severe respiratory conditions leading to hypoxia can increase lactic acidosis risk.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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