GLUCOBAY M-50 10S

About

Glucobay M-50 contains Acarbose, an alpha-glucosidase inhibitor used to manage type 2 diabetes mellitus. Acarbose works by reversibly inhibiting alpha-glucosidase enzymes in the small intestine, which are responsible for breaking down complex carbohydrates into absorbable monosaccharides. By slowing down this digestion process, acarbose delays the absorption of glucose into the bloodstream, thereby reducing postprandial (after-meal) blood glucose spikes.

This medication is typically used as an adjunct to diet and exercise, either alone or in combination with other oral hypoglycemic agents or insulin. It is particularly effective in controlling postprandial hyperglycemia. Acarbose does not stimulate insulin secretion and therefore does not typically cause hypoglycemia when used as monotherapy. Regular monitoring of liver function is recommended, especially during the first year of treatment.

Uses

• To improve glycemic control in adults with type 2 diabetes mellitus.
• As an adjunct to diet and exercise.
• To reduce postprandial blood glucose excursions.
• Can be used as monotherapy or in combination with other antidiabetic agents.

Directions For Use

Take orally with the first bite of each main meal, three times a day, or as directed by your physician.

Benefits

• Specifically targets postprandial glucose spikes.
• Does not cause weight gain.
• Low risk of hypoglycemia when used alone.
• Can be combined with other antidiabetic drugs.
• Improves overall glycemic control.
• Acts locally in the gut, with minimal systemic absorption.

Side Effects

• Flatulence
• Diarrhea
• Abdominal pain
• Bloating
• Nausea
• Vomiting
• Indigestion
• Skin rash
• Elevated liver enzymes (rare)
• Jaundice (rare)
• Ileus (very rare)
• Pneumatosis cystoides intestinalis (very rare)

Safety Measures

• Alcohol - Limit alcohol intake as it can affect blood glucose levels and may exacerbate gastrointestinal side effects.
• Pregnancy - Not recommended during pregnancy due to insufficient data on safety and efficacy.
• Breastfeeding - Not recommended during breastfeeding as it is unknown if acarbose or its metabolites pass into breast milk.
• Liver - Use with caution in patients with liver impairment; regular monitoring of liver enzymes is recommended.
• Kidney - Not recommended for severe kidney impairment (creatinine clearance <25 mL/min) due to limited data.
• Lung - Generally safe for use in patients with lung conditions; no specific contraindications.

Disclaimer

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