About
ALNITRO 6.4 TAB likely contains Isosorbide Mononitrate, an organic nitrate used for the prevention and long-term treatment of angina pectoris (chest pain) due to coronary artery disease. As a vasodilator, it works by relaxing the smooth muscles in the walls of blood vessels, particularly veins and arteries. This relaxation leads to a reduction in both preload (amount of blood returning to the heart) and afterload (resistance the heart must pump against), thereby decreasing the heart's workload and oxygen demand. By improving blood flow to the heart muscle and reducing its oxygen requirements, Isosorbide Mononitrate helps to prevent anginal attacks. The 6.4mg dosage typically indicates an extended-release formulation, designed to provide a sustained therapeutic effect and maintain consistent plasma levels over a longer period, which is crucial for prophylactic use in chronic stable angina.
Uses
- Prevention of angina pectoris.
- Long-term management of coronary artery disease.
- Reduction of frequency and severity of anginal attacks.
- Adjunctive therapy in heart failure (off-label).
Directions For Use
Take orally, usually once daily in the morning, with or without food, or as directed by your physician. Do not crush or chew extended-release tablets.
Benefits
- Reduces frequency of anginal attacks.
- Decreases severity of chest pain.
- Improves exercise tolerance.
- Reduces cardiac workload.
- Provides sustained therapeutic effect.
- Enhances quality of life for angina sufferers.
Side Effects
- Headache (common, often resolves)
- Dizziness
- Lightheadedness
- Flushing
- Nausea
- Hypotension (low blood pressure)
- Tachycardia (increased heart rate)
- Weakness
- Syncope (fainting)
- Rash
- Heartburn
- Blurred vision
Safety Measures
- Alcohol - Avoid alcohol consumption as it can significantly enhance the hypotensive effects of nitrates, leading to severe dizziness and fainting.
- Pregnancy - Use only if clearly needed and the potential benefits outweigh the risks to the fetus. Consult your doctor.
- Breastfeeding - It is unknown if isosorbide mononitrate is excreted in breast milk. Exercise caution and consult your doctor before use.
- Liver - Use with caution in patients with severe liver impairment, as metabolism may be affected. Dose adjustment may be necessary.
- Kidney - Use with caution in patients with severe renal impairment, as excretion may be affected. Dose adjustment may be necessary.
- Lung - Generally considered safe for use in patients with lung conditions. No specific contraindications related to pulmonary function.
Disclaimer
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