OXRA 10MG TAB

About

Oxra tablets contain Dapagliflozin, a highly selective sodium-glucose co-transporter 2 (SGLT2) inhibitor. This medication is primarily used in the management of type 2 diabetes mellitus to improve glycemic control, but its benefits extend significantly beyond blood sugar regulation. Dapagliflozin works by inhibiting SGLT2 in the renal tubules, which is responsible for reabsorbing glucose back into the bloodstream. By blocking this transporter, it promotes the excretion of excess glucose in the urine, thereby lowering blood glucose levels independently of insulin. Furthermore, this mechanism leads to osmotic diuresis, contributing to modest weight loss and blood pressure reduction. Importantly, Dapagliflozin has demonstrated significant cardiovascular and renal protective effects, reducing the risk of hospitalization for heart failure and slowing the progression of chronic kidney disease in a broad range of patients.

Uses

• Treatment of type 2 diabetes mellitus
• Reduction of hospitalization risk for heart failure
• Slowing the progression of chronic kidney disease
• Improvement of glycemic control in adults

Directions For Use

Take one tablet orally once daily, with or without food, preferably in the morning. Swallow the tablet whole with water.

Benefits

• Effectively lowers blood sugar levels
• Reduces the risk of heart failure hospitalization
• Slows the progression of kidney disease
• Promotes modest weight loss
• Helps lower blood pressure
• Reduces cardiovascular mortality

Side Effects

• Genital yeast infections
• Urinary tract infections
• Increased urination
• Thirst
• Dizziness
• Low blood pressure
• Kidney problems
• Ketoacidosis (rare)
• Fournier's gangrene (very rare)
• Back pain
• Nausea
• Constipation

Safety Measures

• Alcohol - Limit alcohol intake as it can increase the risk of dehydration and affect blood sugar levels. Monitor closely.
• Pregnancy - Not recommended during the second and third trimesters due to potential adverse effects on fetal kidney development. Consult your doctor.
• Breastfeeding - Not recommended during breastfeeding as it may pass into breast milk and affect the infant. Consult your doctor.
• Liver - No dose adjustment is typically needed for mild to moderate hepatic impairment. Use with caution in severe impairment.
• Kidney - Dose adjustment or discontinuation may be necessary based on eGFR. Not recommended for severe renal impairment or dialysis.
• Lung - Generally safe for use in patients with lung conditions. No specific precautions related to pulmonary function.

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