GLUCORYL MV-2 10S

About

GLUCORYL MV-2 is a comprehensive triple-combination oral antidiabetic medication designed for the effective management of type 2 diabetes mellitus. It contains Glimepiride, a sulfonylurea that stimulates insulin secretion from pancreatic beta cells; Metformin, a biguanide that reduces hepatic glucose production, decreases intestinal glucose absorption, and improves insulin sensitivity; and Voglibose, an alpha-glucosidase inhibitor that delays the digestion and absorption of carbohydrates in the small intestine, thereby reducing postprandial blood glucose excursions. This synergistic combination targets multiple pathophysiological defects in type 2 diabetes, providing robust glycemic control by addressing both fasting and post-meal blood sugar levels, particularly when dual therapy or monotherapy is insufficient to achieve target blood glucose levels.

Uses

• Management of type 2 diabetes mellitus.
• Improvement of glycemic control.
• When diet and exercise alone are not enough.
• As an add-on therapy to other antidiabetic agents.

Directions For Use

Take orally with meals, usually once or twice daily, as directed by your physician. Swallow the tablet whole with water.

Benefits

• Comprehensive blood sugar control.
• Targets multiple pathways of glucose metabolism.
• Reduces both fasting and post-meal glucose.
• Improved insulin sensitivity.
• May lead to modest weight loss (Metformin effect).
• Convenient fixed-dose combination.

Side Effects

• Hypoglycemia (especially with Glimepiride)
• Nausea
• Diarrhea
• Abdominal pain/discomfort
• Flatulence
• Bloating
• Headache
• Dizziness
• Lactic acidosis (rare, Metformin)
• Vitamin B12 deficiency (long-term Metformin)
• Skin reactions
• Transient visual disturbances

Safety Measures

• Alcohol - Avoid excessive alcohol consumption as it can increase the risk of lactic acidosis (Metformin) and hypoglycemia (Glimepiride).
• Pregnancy - Generally not recommended during pregnancy. Consult your doctor to discuss risks and alternative treatments.
• Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk. Seek medical advice.
• Liver - Contraindicated in severe hepatic impairment due to increased risk of lactic acidosis (Metformin) and potential for Glimepiride accumulation.
• Kidney - Contraindicated in severe renal impairment (eGFR <30 mL/min/1.73m²) due to Metformin accumulation and increased risk of lactic acidosis.
• Lung - Use with caution in conditions causing hypoxia, such as severe respiratory failure, as it may increase the risk of lactic acidosis.

Disclaimer

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