GLYREE M1 TAB 10 S

About

Glyree M1 combines Glimepiride 1mg, a sulfonylurea, and Metformin, a biguanide, offering a synergistic approach to the management of type 2 diabetes mellitus. Glimepiride primarily acts by stimulating the beta cells in the pancreas to increase insulin secretion, which helps to lower elevated blood glucose levels. Metformin complements this action by reducing the liver's production of glucose and enhancing the body's sensitivity to insulin, allowing cells to more effectively absorb glucose from the bloodstream. This dual mechanism addresses both the insulin deficiency and insulin resistance often seen in type 2 diabetes. It is typically prescribed when diet and exercise alone, or monotherapy with either component, are insufficient to achieve optimal glycemic control, thereby helping to prevent long-term complications.

Uses

• Treatment of type 2 diabetes mellitus.
• To improve blood glucose control.
• When diet and exercise alone are not enough.
• As an adjunct to lifestyle modifications.

Directions For Use

Take orally with meals, usually once or twice daily, as directed by your physician.

Benefits

• Effective reduction in blood sugar levels.
• Improved HbA1c.
• Enhanced insulin secretion.
• Reduced glucose production by the liver.
• Improved insulin sensitivity.
• Convenient combination therapy.

Side Effects

• Hypoglycemia
• Nausea
• Diarrhea
• Vomiting
• Abdominal pain
• Metallic taste
• Headache
• Dizziness
• Skin rash
• Weight gain (less common with metformin component)
• Rarely, lactic acidosis
• Rarely, blood dyscrasias

Safety Measures

• Alcohol - Avoid excessive alcohol intake as it can increase the risk of hypoglycemia with glimepiride and lactic acidosis with metformin.
• Pregnancy - Not recommended during pregnancy. Insulin is generally preferred for glycemic control in pregnant women. Consult your doctor.
• Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk. Consult your doctor.
• Liver - Use with caution in patients with liver impairment; metformin is contraindicated in severe hepatic dysfunction due to increased risk of lactic acidosis.
• Kidney - Contraindicated in severe renal impairment. Dose adjustment is necessary for moderate renal impairment.
• Lung - Generally safe, but caution is advised in patients with severe acute respiratory failure due to increased risk of lactic acidosis with metformin.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.