Immunorel 5% 100ml

About

Intravenous Immunoglobulin (IVIG) is a highly purified, sterile solution comprising human antibodies, predominantly immunoglobulin G (IgG), meticulously derived from the pooled plasma of thousands of healthy donors. This therapeutic agent is widely utilized across a broad spectrum of clinical indications, encompassing both primary and secondary immune deficiencies, as well as various autoimmune and inflammatory disorders. The multifaceted mechanism of action of IVIG involves providing passive immunity, effectively modulating the immune system, and neutralizing pathogenic antibodies or toxins. Key immunological effects include the saturation of Fc receptors on immune cells, suppression of autoantibody production, and the alteration of cytokine profiles, which collectively contribute to its therapeutic efficacy. This makes IVIG an indispensable and versatile treatment option for complex conditions characterized by significant immune system dysregulation, aiming to restore immune homeostasis and mitigate disease progression.

Uses

• Primary immunodeficiency diseases (PID).
• Idiopathic thrombocytopenic purpura (ITP).
• Kawasaki disease.
• Chronic inflammatory demyelinating polyneuropathy (CIDP).

Directions For Use

Administered intravenously by a healthcare professional. Dosage and infusion rate are determined by the patient's condition and body weight.

Benefits

• Provides broad-spectrum passive immunity.
• Modulates dysfunctional immune responses.
• Reduces severity and frequency of infections.
• Effective in various autoimmune conditions.
• Can prevent complications in certain diseases.
• Generally well-tolerated when administered correctly.

Side Effects

• Headache
• Fever
• Chills
• Nausea
• Vomiting
• Fatigue
• Dizziness
• Rash
• Muscle pain
• Back pain
• Hypotension (during infusion)
• Aseptic meningitis (rare)

Safety Measures

• Alcohol - No specific interaction with alcohol is known, but general health and hydration are important during treatment.
• Pregnancy - Generally considered safe during pregnancy, as immunoglobulins are naturally present. Consult a doctor for specific guidance.
• Breastfeeding - Immunoglobulins are naturally present in breast milk and are generally considered safe. Consult a doctor.
• Liver - Use with caution in patients with pre-existing liver conditions, though direct hepatotoxicity is rare.
• Kidney - Use with caution in patients with renal impairment, especially with high doses or rapid infusion rates, due to potential for acute kidney injury.
• Lung - Use with caution in patients with pre-existing pulmonary conditions, as rare cases of transfusion-related acute lung injury (TRALI) have been reported.

Disclaimer

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