About
Jardiance Met is a combination medication containing empagliflozin and metformin hydrochloride, indicated for the management of type 2 diabetes mellitus in adults. Empagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that reduces glucose reabsorption in the kidneys, leading to increased glucose excretion in the urine and lower blood glucose levels. Metformin, a biguanide, primarily works by decreasing hepatic glucose production, reducing intestinal glucose absorption, and improving insulin sensitivity.
This synergistic combination provides comprehensive glycemic control, helping to lower HbA1c levels effectively. Jardiance Met is used as an adjunct to diet and exercise. It has also demonstrated cardiovascular benefits, including a reduction in the risk of cardiovascular death and hospitalization for heart failure in patients with type 2 diabetes and established cardiovascular disease. Regular monitoring of kidney function and vitamin B12 levels is important during treatment.
Uses
- To improve glycemic control in adults with type 2 diabetes mellitus.
- As an adjunct to diet and exercise.
- To reduce the risk of cardiovascular death and hospitalization for heart failure.
- When both empagliflozin and metformin are appropriate for treatment.
Directions For Use
Take orally twice daily with meals to minimize gastrointestinal side effects, or as prescribed by your doctor.
Benefits
- Provides dual-action blood glucose lowering.
- Significantly reduces HbA1c levels.
- Offers cardiovascular and renal benefits.
- May lead to modest weight loss.
- Improves insulin sensitivity.
- Convenient combination therapy.
Side Effects
- Diarrhea
- Nausea
- Vomiting
- Abdominal discomfort
- Urinary tract infections
- Genital yeast infections
- Increased urination
- Hypoglycemia (when used with insulin or sulfonylureas)
- Lactic acidosis (rare, but serious)
- Ketoacidosis (rare)
- Vitamin B12 deficiency
- Kidney problems
Safety Measures
- Alcohol - Avoid excessive alcohol intake as it can increase the risk of lactic acidosis and hypoglycemia.
- Pregnancy - Not recommended during pregnancy, especially in the second and third trimesters, due to potential fetal kidney effects.
- Breastfeeding - Not recommended during breastfeeding as both components can pass into breast milk.
- Liver - Use with caution in liver impairment; contraindicated in severe liver disease due to lactic acidosis risk.
- Kidney - Contraindicated in severe kidney impairment (eGFR <30 mL/min/1.73 m²); dose adjustments for moderate impairment.
- Lung - Generally safe, but acute/chronic lung disease with hypoxia can increase lactic acidosis risk with metformin.
Disclaimer
MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.
Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
| Shipping Cost |
|
| Shop Location | Assam, India |
No comments found for this product. Be the first to comment!