Lenced 10mg Capsule

About

Lenalidomide, an immunomodulatory drug, is primarily utilized in the treatment of specific hematological malignancies. It exerts its therapeutic effects through multiple mechanisms, including direct anti-tumor activity, inhibition of angiogenesis, and modulation of the immune system. The drug works by selectively degrading specific proteins crucial for cancer cell proliferation and survival, leading to programmed cell death and suppression of tumor growth. It also enhances the activity of natural killer cells and T-cells, contributing to its overall immunomodulatory profile.

This medication is often prescribed either as a monotherapy or in combination with other therapeutic agents, depending on the specific disease indication and the patient's clinical status. Its targeted action helps to improve patient outcomes by disrupting key pathways involved in cancer progression, making it a valuable component in the management of certain advanced cancers.

Uses

• Treatment of Multiple Myeloma (MM)
• Management of Myelodysplastic Syndromes (MDS) with del(5q)
• Therapy for Mantle Cell Lymphoma (MCL)
• Treatment of Follicular Lymphoma (FL)

Directions For Use

Take this medication orally as directed by your physician, usually once daily with or without food. Do not crush, chew, or open the capsule.

Benefits

• Effective in treating various hematological cancers.
• Improves overall survival in multiple myeloma patients.
• Reduces transfusion dependence in specific MDS cases.
• Offers a targeted approach to cancer therapy.
• Can be used effectively in combination or as monotherapy.
• Helps to modulate the immune system against cancer cells.

Side Effects

• Fatigue
• Diarrhea
• Nausea
• Constipation
• Rash
• Peripheral neuropathy
• Thrombocytopenia
• Neutropenia
• Anemia
• Deep vein thrombosis (DVT)
• Pulmonary embolism (PE)
• Muscle cramps

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it may exacerbate certain side effects like fatigue or gastrointestinal issues.
• Pregnancy - Lenalidomide is highly teratogenic and absolutely contraindicated in pregnancy. Women of childbearing potential must use highly effective contraception.
• Breastfeeding - It is not recommended during breastfeeding due to the potential for serious adverse effects in the infant.
• Liver - Use with caution in patients with hepatic impairment; dose adjustments may be necessary. Monitor liver function regularly.
• Kidney - Dose adjustments are typically required for patients with renal impairment due to its primary renal excretion. Monitor kidney function closely.
• Lung - Use with caution in patients with pre-existing lung conditions, as pulmonary events like interstitial lung disease can occur.

Disclaimer

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