Letrovin 2.5mg Tablet

About

Letrovin 2.5mg Tablet is an oral medication belonging to the class of aromatase inhibitors. It functions by selectively inhibiting the enzyme aromatase, which is responsible for converting androgens into estrogens in peripheral tissues. In postmenopausal women, where ovarian estrogen production has ceased, aromatase is the primary source of circulating estrogens. By significantly reducing estrogen levels, Letrovin 2.5mg helps to suppress the growth of hormone-receptor-positive breast cancers, which are stimulated by estrogen.

This medication is primarily used in the treatment of early and advanced breast cancer in postmenopausal women. Its efficacy stems from its ability to deprive estrogen-sensitive tumor cells of the growth-promoting hormone. Treatment with Letrovin 2.5mg is typically long-term, often extending for several years, to prevent recurrence and improve disease-free survival. Regular monitoring for bone mineral density and lipid profiles is recommended due to potential side effects associated with estrogen deprivation.

Uses

• Adjuvant treatment of early hormone-receptor-positive breast cancer in postmenopausal women.
• Extended adjuvant treatment of hormone-receptor-positive breast cancer in postmenopausal women who have completed standard tamoxifen therapy.
• First-line treatment of hormone-receptor-positive advanced breast cancer in postmenopausal women.
• Treatment of advanced breast cancer in postmenopausal women after anti-estrogen therapy.

Directions For Use

Take one tablet orally once daily, with or without food. Follow your doctor's instructions precisely.

Benefits

• Significantly reduces estrogen levels in postmenopausal women.
• Inhibits the growth of hormone-receptor-positive breast cancer cells.
• Reduces the risk of breast cancer recurrence.
• Improves disease-free survival in early breast cancer.
• Effective in both early and advanced breast cancer settings.
• Offers a convenient oral once-daily dosing regimen.

Side Effects

• Hot flashes.
• Joint pain (arthralgia).
• Fatigue.
• Nausea.
• Headache.
• Dizziness.
• Bone pain.
• Osteoporosis and fractures.
• Hair thinning.
• Increased sweating.
• Vaginal dryness.
• Elevated cholesterol levels.

Safety Measures

• Alcohol - Moderate alcohol consumption is generally considered safe, but discuss with your doctor as it may affect overall health during cancer treatment.
• Pregnancy - Absolutely contraindicated in pregnant women due to potential harm to the fetus. Effective contraception must be used by premenopausal women.
• Breastfeeding - Contraindicated during breastfeeding as it is unknown if it passes into breast milk and could harm the infant.
• Liver - Use with caution in patients with severe liver impairment. Dosage adjustments may be necessary.
• Kidney - Generally no dosage adjustment is required for mild to moderate renal impairment. Use with caution in severe renal impairment.
• Lung - No specific precautions for lung conditions are typically required.

Disclaimer

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