Mapsplatin 100mg Injection

About

Mapsplatin 100mg Injection contains cisplatin, a potent platinum-based chemotherapy agent widely used in oncology. Its mechanism of action involves forming DNA adducts, which leads to DNA damage and inhibition of DNA synthesis and repair in rapidly dividing cancer cells. This ultimately triggers apoptosis, or programmed cell death, effectively halting tumor growth. Cisplatin is a highly effective cytotoxic drug, often administered as part of combination chemotherapy regimens for various solid tumors. Due to its significant efficacy, it remains a cornerstone in the treatment protocols for several aggressive malignancies, despite its notable side effect profile which necessitates careful patient monitoring and supportive care.

Uses

• Treatment of testicular cancer.
• Treatment of ovarian cancer.
• Treatment of bladder cancer.
• Treatment of head and neck cancer.

Directions For Use

This medication is administered intravenously by a healthcare professional. It is typically given in cycles, with specific dosing based on your condition.

Benefits

• Effective against a wide range of solid tumors.
• Often used in combination chemotherapy regimens.
• Can achieve complete remission in some cancers.
• Improves survival rates in specific malignancies.
• Well-established efficacy in oncology.
• Critical component of curative regimens for certain cancers.

Side Effects

• Severe nausea and vomiting
• Nephrotoxicity (kidney damage)
• Ototoxicity (hearing loss, tinnitus)
• Myelosuppression (low blood counts)
• Peripheral neuropathy
• Electrolyte disturbances (hypomagnesemia)
• Anaphylactic-like reactions
• Fatigue
• Hair loss (alopecia)
• Mucositis
• Diarrhea
• Taste alteration

Safety Measures

• Alcohol - Avoid or limit alcohol; it can exacerbate gastrointestinal side effects and potentially increase liver strain during treatment.
• Pregnancy - Contraindicated during pregnancy; cisplatin is highly teratogenic and embryotoxic, causing severe fetal harm.
• Breastfeeding - Not recommended; cisplatin passes into breast milk and can cause serious adverse effects in a nursing infant.
• Liver - Use with caution; monitor liver function, though primary toxicity is renal.
• Kidney - Contraindicated in severe renal impairment; requires aggressive hydration and close monitoring of kidney function.
• Lung - Use with caution in pre-existing lung conditions; pulmonary fibrosis is a rare but serious side effect.

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