NUCOXIA 60MG TAB

About

Etoricoxib is a potent and highly selective cyclooxygenase-2 (COX-2) inhibitor, belonging to the class of non-steroidal anti-inflammatory drugs (NSAIDs). Its therapeutic action is achieved by selectively blocking the COX-2 enzyme, which is primarily induced at sites of inflammation and is responsible for the synthesis of prostaglandins that mediate pain, inflammation, and fever. By specifically targeting COX-2, etoricoxib provides significant anti-inflammatory, analgesic, and antipyretic effects while aiming to reduce the gastrointestinal side effects commonly associated with non-selective NSAIDs that inhibit both COX-1 and COX-2. It is widely used for the symptomatic relief of various acute and chronic inflammatory and painful conditions, offering effective and sustained pain management for patients with conditions like osteoarthritis, rheumatoid arthritis, and acute gouty arthritis.

Uses

• Symptomatic relief of osteoarthritis.
• Symptomatic relief of rheumatoid arthritis.
• Treatment of ankylosing spondylitis.
• Management of acute gouty arthritis.

Directions For Use

Take orally once daily, with or without food, as prescribed by your doctor.
Swallow the tablet whole with water.

Benefits

• Effective pain relief and anti-inflammatory action.
• Selective COX-2 inhibition may reduce GI side effects.
• Long duration of action allows for once-daily dosing.
• Improves joint function and reduces stiffness.
• Suitable for chronic inflammatory conditions.
• Provides symptomatic relief for acute pain episodes.

Side Effects

• Abdominal pain
• Diarrhea
• Nausea
• Headache
• Dizziness
• Peripheral edema
• Hypertension
• Dyspepsia
• Heartburn
• Fatigue
• Flu-like symptoms
• Increased risk of cardiovascular thrombotic events (serious)

Safety Measures

• Alcohol - Concomitant use of alcohol with etoricoxib can increase the risk of gastrointestinal irritation and bleeding. It is advisable to limit or avoid alcohol consumption.
• Pregnancy - Etoricoxib is contraindicated in the third trimester of pregnancy and should be avoided in early pregnancy due to potential risks to the fetus. Consult a doctor.
• Breastfeeding - Etoricoxib is excreted in human milk. Breastfeeding should be discontinued during treatment with etoricoxib due to potential adverse effects on the infant.
• Liver - Use with caution in patients with hepatic impairment. Etoricoxib is contraindicated in severe hepatic dysfunction. Liver function should be monitored.
• Kidney - Use with caution in patients with renal impairment, as NSAIDs can cause dose-dependent renal toxicity. Monitor renal function closely.
• Lung - Use with caution in patients with asthma, especially aspirin-sensitive asthma, as etoricoxib can precipitate bronchospasm.

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