NUCOXIA 90MG TAB

About

Etoricoxib, marketed as NUCOXIA 90MG TAB, is a selective cyclooxygenase-2 (COX-2) inhibitor belonging to the non-steroidal anti-inflammatory drug (NSAID) class. It is indicated for the symptomatic relief of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and for the treatment of acute gouty arthritis and acute pain, including post-operative dental pain. By selectively inhibiting COX-2, etoricoxib reduces the production of prostaglandins, which are mediators of pain and inflammation, while minimizing the gastrointestinal side effects often associated with non-selective NSAIDs that also inhibit COX-1.

This selectivity aims to provide effective pain relief and reduce inflammation with a potentially improved gastrointestinal safety profile compared to traditional NSAIDs. However, like all NSAIDs, it carries cardiovascular risks, especially with long-term use or in patients with pre-existing cardiovascular disease.

Uses

• Symptomatic relief of osteoarthritis.
• Treatment of rheumatoid arthritis and ankylosing spondylitis.
• Management of acute gouty arthritis.
• Relief of acute pain, including post-operative dental pain.

Directions For Use

Take one tablet orally once daily, with or without food, as prescribed by your doctor. Do not exceed the recommended dose.

Benefits

• Effective pain relief and anti-inflammatory action.
• Selective COX-2 inhibition, potentially reducing GI side effects.
• Long-lasting effect, allowing once-daily dosing.
• Useful for various chronic inflammatory conditions.
• Reduces swelling and stiffness in joints.
• Provides relief for acute pain episodes.

Side Effects

• Abdominal pain
• Diarrhea
• Nausea
• Indigestion
• Headache
• Dizziness
• Edema (fluid retention)
• Hypertension (high blood pressure)
• Palpitations
• Fatigue
• Flu-like symptoms
• Upper respiratory tract infection

Safety Measures

• Alcohol - Avoid excessive alcohol consumption as it can increase the risk of gastrointestinal irritation and bleeding when combined with NSAIDs.
• Pregnancy - Not recommended during pregnancy, especially in the third trimester, due to potential fetal harm and complications.
• Breastfeeding - Avoid during breastfeeding as etoricoxib may pass into breast milk and could harm the infant.
• Liver - Use with caution in patients with mild to moderate hepatic impairment; contraindicated in severe liver disease.
• Kidney - Use with caution in patients with renal impairment; monitor kidney function closely as NSAIDs can worsen renal function.
• Lung - Use with caution in patients with asthma, as NSAIDs can trigger bronchospasm in susceptible individuals.

Disclaimer

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