About
RENODAPT S 360 Tablets contain Mycophenolic Acid (MPA) 360mg, an enteric-coated formulation of an immunosuppressant medication. It is primarily used to prevent organ rejection in patients who have received kidney, heart, or liver transplants. MPA works by selectively inhibiting inosine monophosphate dehydrogenase (IMPDH), an enzyme crucial for the de novo synthesis of guanosine nucleotides, which are essential for the proliferation of B and T lymphocytes. This selective inhibition suppresses the immune response without causing significant myelosuppression.
The enteric-coated formulation helps to reduce gastrointestinal side effects often associated with mycophenolate mofetil. RENODAPT S 360 is typically used in combination with other immunosuppressants, such as calcineurin inhibitors and corticosteroids, to provide comprehensive immune suppression and minimize the risk of graft rejection. Regular monitoring of blood counts and kidney function is important during treatment to manage potential side effects and ensure optimal therapeutic levels.
Uses
- Prevention of kidney transplant rejection
- Prevention of heart transplant rejection
- Prevention of liver transplant rejection
- Treatment of refractory rejection in some cases
Directions For Use
Take orally twice daily on an empty stomach, at least one hour before or two hours after food, as directed by your transplant physician. Swallow whole, do not crush or chew.
Benefits
- Effective in preventing organ rejection
- Reduces gastrointestinal side effects (enteric-coated)
- Often used in combination for enhanced immunosuppression
- Improves long-term graft survival
- Helps maintain quality of life post-transplant
- Supports stable immune suppression
Side Effects
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Leukopenia (low white blood cell count)
- Anemia
- Thrombocytopenia (low platelet count)
- Increased risk of infections
- Hypertension (high blood pressure)
- Headache
- Tremor
- Insomnia
Safety Measures
- Alcohol - No direct interaction, but alcohol can worsen overall health and immune function in transplant patients. Consult your doctor.
- Pregnancy - Mycophenolic acid is highly teratogenic and can cause severe birth defects. It is contraindicated in pregnancy. Effective contraception is mandatory.
- Breastfeeding - Mycophenolic acid is excreted in breast milk. Breastfeeding is contraindicated due to potential serious adverse effects on the infant.
- Liver - Use with caution in patients with severe liver impairment; dosage adjustments may be necessary.
- Kidney - Use with caution in patients with severe kidney impairment; dosage adjustments may be necessary.
- Lung - Use with caution in patients with pre-existing lung conditions, as mycophenolic acid can rarely cause interstitial lung disease.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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| Shop Location | Assam, India |
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