SILDURA 8/0.5MG 10

About

SILDURA 8/0.5MG combines Tamsulosin and Dutasteride, providing comprehensive management for benign prostatic hyperplasia (BPH). Tamsulosin, an alpha-1 blocker, acts by relaxing the smooth muscles in the prostate and bladder neck, leading to a rapid improvement in urinary flow and a reduction in bothersome lower urinary tract symptoms (LUTS) associated with BPH. Dutasteride, a 5-alpha-reductase inhibitor, works by inhibiting the enzyme responsible for converting testosterone into dihydrotestosterone (DHT), the primary androgen driving prostate growth. This action effectively reduces the size of the enlarged prostate over time, thereby addressing the root cause of BPH and decreasing the risk of BPH-related complications such as acute urinary retention and the need for surgical intervention. This combination therapy is particularly beneficial for men with moderate to severe BPH symptoms and an enlarged prostate.

Uses

• Management of symptomatic benign prostatic hyperplasia (BPH)
• Alleviation of lower urinary tract symptoms (LUTS) due to BPH
• Reduction of prostate volume in men with enlarged prostates
• Prevention of BPH progression and related complications

Directions For Use

Take one capsule orally once daily, approximately 30 minutes after the same meal each day. Swallow the capsule whole; do not crush, chew, or open it.

Benefits

• Offers rapid relief of urinary symptoms
• Reduces prostate gland size effectively
• Decreases the risk of BPH-related surgery
• Prevents acute urinary retention
• Improves overall urinary function
• Provides long-term disease management

Side Effects

• Dizziness or lightheadedness
• Ejaculation disorders
• Decreased sexual drive
• Impotence (erectile dysfunction)
• Breast enlargement or tenderness
• Orthostatic hypotension
• Headache
• Nausea
• Diarrhea
• Runny or stuffy nose
• Skin rash or itching
• Hair loss or growth (rare)

Safety Measures

• Alcohol - Concurrent use of alcohol may enhance the hypotensive effects and increase dizziness. Avoid excessive alcohol intake.
• Pregnancy - Dutasteride is teratogenic and can cause abnormalities in a male fetus. Pregnant women should not handle broken capsules.
• Breastfeeding - This medication is not indicated for use in women and should not be used during breastfeeding.
• Liver - Exercise caution in patients with hepatic impairment, as both active ingredients are extensively metabolized by the liver.
• Kidney - No specific dose adjustment is typically needed for mild to moderate renal impairment. Use with caution in severe cases.
• Lung - This medication is not known to have significant direct adverse effects on pulmonary function.

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