About
SILOFAST 8MG typically refers to Silodosin, an alpha-1A adrenergic receptor antagonist used for the treatment of signs and symptoms of benign prostatic hyperplasia (BPH). Silodosin works by selectively blocking alpha-1A adrenergic receptors located primarily in the prostate, bladder neck, and urethra. This blockade leads to the relaxation of the smooth muscles in these areas, thereby reducing the dynamic component of prostatic obstruction. The relaxation of these muscles improves urine flow and alleviates bothersome lower urinary tract symptoms (LUTS) associated with BPH, such as hesitancy, weak stream, incomplete emptying, and frequent or urgent urination.
Unlike some other alpha-blockers, Silodosin's high selectivity for alpha-1A receptors is thought to contribute to a lower incidence of cardiovascular side effects like orthostatic hypotension, although it can still occur. Its rapid onset of action provides quick symptomatic relief, making it a valuable option for men seeking to improve their quality of life by managing their BPH symptoms effectively. It is generally prescribed for men with moderate to severe BPH symptoms.
Uses
- Treatment of benign prostatic hyperplasia (BPH)
- Improvement of lower urinary tract symptoms (LUTS)
- Enhancement of urine flow in men with BPH
- Relief from urinary hesitancy and urgency
Directions For Use
Take one tablet orally once daily with a meal, as directed by your healthcare provider. Swallow the tablet whole.
Benefits
- Provides rapid relief from BPH symptoms
- Significantly improves urinary flow
- Reduces urinary frequency and urgency
- Helps in complete bladder emptying
- Enhances overall quality of life
- Generally well-tolerated with selective action
Side Effects
- Retrograde ejaculation
- Dizziness
- Orthostatic hypotension
- Headache
- Nasal congestion
- Diarrhea
- Insomnia
- Fatigue
- Nausea
- Dry mouth
- Abdominal pain
- Palpitations
Safety Measures
- Alcohol - Alcohol can increase the risk of dizziness and orthostatic hypotension. It is advisable to limit or avoid alcohol consumption while on this medication.
- Pregnancy - This medication is not indicated for use in women and should not be used during pregnancy.
- Breastfeeding - This medication is not indicated for use in women and should not be used by breastfeeding mothers.
- Liver - Use with caution in patients with moderate hepatic impairment. It is contraindicated in severe hepatic impairment.
- Kidney - Use with caution in patients with moderate renal impairment. It is contraindicated in severe renal impairment.
- Lung - Generally safe for use in patients with lung conditions, but caution is advised if severe respiratory issues are present and could be exacerbated by potential hypotensive effects.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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