Sutekast 50mg Capsule 7's

About

Sutekast 50mg Capsule is an oral multi-targeted receptor tyrosine kinase inhibitor (TKI) indicated for the treatment of various advanced cancers. It functions by blocking multiple receptor tyrosine kinases, including vascular endothelial growth factor receptors (VEGFRs), platelet-derived growth factor receptors (PDGFRs), and KIT, which are crucial for tumor angiogenesis, cell proliferation, and survival. By inhibiting these pathways, Sutekast effectively impedes tumor growth, metastasis, and the development of new blood vessels that supply tumors.

This targeted therapy offers a specific approach to cancer treatment, focusing on molecular pathways that are often dysregulated in malignant cells. Its mechanism of action helps to slow disease progression and can lead to tumor regression in responsive patients. Due to its potent activity and broad spectrum of kinase inhibition, Sutekast requires careful patient selection and monitoring for potential adverse effects, ensuring optimal therapeutic outcomes while managing toxicity.

Uses

• Treatment of advanced renal cell carcinoma (RCC).
• Management of imatinib-resistant or intolerant gastrointestinal stromal tumors (GIST).
• Therapy for advanced pancreatic neuroendocrine tumors (pNET).
• Used in certain other advanced solid tumors as per clinical guidelines.

Directions For Use

Take orally once daily with or without food, as directed by your oncologist. Do not open, crush, or chew the capsule.

Benefits

• Targets multiple pathways critical for cancer growth.
• Effective in slowing tumor progression.
• May lead to tumor shrinkage in some patients.
• Improves progression-free survival in specific cancers.
• Oral administration offers convenience.
• Provides a targeted therapy option for advanced malignancies.

Side Effects

• Fatigue and asthenia.
• Diarrhea and nausea.
• Stomatitis (mouth sores).
• Hand-foot syndrome (palmar-plantar erythrodysesthesia).
• Hypertension (high blood pressure).
• Skin rash and discoloration.
• Altered taste sensation.
• Abdominal pain.
• Headache.
• Hair discoloration or thinning.
• Hypothyroidism.
• Vomiting.

Safety Measures

• Alcohol - Avoid or limit alcohol consumption due to potential for increased liver toxicity and exacerbation of gastrointestinal side effects.
• Pregnancy - Contraindicated; Sutekast can cause fetal harm. Women of childbearing potential must use effective contraception during treatment and for a period after.
• Breastfeeding - Contraindicated; it is unknown if Sutekast is excreted in human milk, but due to potential for serious adverse reactions in breastfed infants, breastfeeding should be discontinued.
• Liver - Use with caution in patients with hepatic impairment. Dose adjustments may be necessary, and liver function tests should be monitored regularly.
• Kidney - Use with caution in patients with renal impairment. Dose adjustments may be required, and kidney function should be closely monitored.
• Lung - Monitor for signs and symptoms of interstitial lung disease (ILD) or pneumonitis, a rare but potentially severe adverse event.

Disclaimer

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