About
Telmisartan/Metoprolol Succinate, marketed as Telvas Beta, is a combination medication used for the treatment of essential hypertension, particularly when monotherapy is insufficient. Telmisartan is an angiotensin II receptor blocker (ARB) that selectively blocks the AT1 receptor, leading to vasodilation and reduced blood pressure. Metoprolol succinate is a selective beta-1 adrenergic blocker that reduces heart rate, myocardial contractility, and renin release, thereby lowering blood pressure and cardiac workload. This combination provides a comprehensive approach to blood pressure control by addressing multiple pathways involved in hypertension, offering synergistic effects and potentially better tolerability compared to higher doses of individual components. It is particularly beneficial for patients with co-existing conditions like angina or post-myocardial infarction, providing both blood pressure control and cardiac protection.
Uses
- Treatment of essential hypertension.
- When monotherapy is insufficient for blood pressure control.
- To reduce cardiovascular risk in hypertensive patients.
- Management of hypertension with co-existing angina.
Directions For Use
Take orally once daily, preferably at the same time each day, with or without food, as directed by your doctor.
Benefits
- Provides effective and sustained blood pressure reduction.
- Combines two complementary antihypertensive mechanisms.
- Offers convenient once-daily dosing.
- Reduces heart rate and cardiac workload.
- Beneficial for patients with angina or post-MI.
- May improve overall cardiovascular outcomes.
Side Effects
- Dizziness
- Fatigue
- Bradycardia (slow heart rate)
- Hypotension (low blood pressure)
- Headache
- Nausea
- Diarrhea
- Cold extremities
- Shortness of breath (especially in susceptible patients)
- Insomnia
- Depression
- Erectile dysfunction
Safety Measures
- Alcohol - Alcohol can enhance the hypotensive and sedative effects; use with caution and avoid excessive intake.
- Pregnancy - Contraindicated in pregnancy due to potential fetal harm from telmisartan (renal dysfunction, oligohydramnios).
- Breastfeeding - Not recommended during breastfeeding as components may pass into breast milk and harm the infant.
- Liver - Use with caution in hepatic impairment; dose adjustment may be necessary, especially for telmisartan.
- Kidney - Use with caution in renal impairment; monitor kidney function and potassium levels regularly.
- Lung - Use with caution in patients with bronchospastic diseases (e.g., asthma, COPD) due to metoprolol's beta-blocking effects.
Disclaimer
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