TENEZA TAB

About

TENEZA TAB contains Teneligliptin, an oral antidiabetic medication belonging to the dipeptidyl peptidase-4 (DPP-4) inhibitor class. It is used in the management of type 2 diabetes mellitus to improve glycemic control. Teneligliptin works by inhibiting the enzyme DPP-4, which is responsible for the inactivation of incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). By preventing the breakdown of these incretins, Teneligliptin increases their levels, leading to enhanced glucose-dependent insulin secretion from pancreatic beta cells and reduced glucagon secretion from pancreatic alpha cells. This results in lower fasting and post-meal blood glucose levels without significantly increasing the risk of hypoglycemia when used as monotherapy.

Uses

• Management of type 2 diabetes mellitus.
• Improvement of glycemic control in adults.
• Used as monotherapy or in combination with other antidiabetic agents.
• Reduction of fasting and postprandial blood glucose levels.

Directions For Use

Take one tablet orally once daily, preferably before a meal, or as directed by your physician.

Benefits

• Effectively lowers blood glucose levels.
• Low risk of hypoglycemia as monotherapy.
• Weight-neutral effect.
• Convenient once-daily dosing.
• Improves pancreatic beta-cell function.
• Well-tolerated in most patients.

Side Effects

• Headache
• Nasopharyngitis
• Upper respiratory tract infection
• Diarrhea
• Constipation
• Abdominal discomfort
• Rash
• Urticaria
• Dizziness
• Fatigue
• Pancreatitis (rare)
• Hypoglycemia (when combined with sulfonylureas or insulin)

Safety Measures

• Alcohol - Alcohol consumption should be moderate as it can affect blood sugar levels.
• Pregnancy - Not recommended during pregnancy; consult a doctor for alternative treatments.
• Breastfeeding - Avoid during breastfeeding as it may pass into breast milk; seek medical advice.
• Liver - Use with caution in patients with severe liver impairment; dose adjustment may be needed.
• Kidney - Generally safe in kidney conditions, but dose adjustment may be required in severe renal impairment.
• Lung - No specific contraindications or precautions related to lung conditions.

Disclaimer

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