TETAN AM 40 15

About

TETAN AM 40 combines Telmisartan, an angiotensin II receptor blocker (ARB), with Amlodipine, a dihydropyridine calcium channel blocker, for the effective management of essential hypertension. Telmisartan works by selectively blocking the binding of angiotensin II to its AT1 receptors, leading to vasodilation, reduced aldosterone secretion, and a decrease in blood pressure. This action also helps to protect target organs from the damaging effects of high blood pressure. Amlodipine exerts its antihypertensive effect by relaxing the smooth muscle in the walls of blood vessels, primarily arteries, which reduces peripheral vascular resistance and lowers blood pressure. It also improves blood flow to the heart.

This combination therapy is particularly beneficial for patients who require more aggressive blood pressure control or who have not achieved their target blood pressure with monotherapy. The complementary mechanisms of action of Telmisartan and Amlodipine provide sustained and potent antihypertensive effects, reducing the risk of cardiovascular events such as stroke, myocardial infarction, and heart failure. It is a well-tolerated option for long-term blood pressure management, offering comprehensive cardiovascular protection.

Uses

• Management of essential hypertension.
• Reduction of cardiovascular risk in high-risk patients.
• Treatment of hypertension unresponsive to single-agent therapy.
• Improvement of blood flow in certain vascular conditions.

Directions For Use

Take orally as directed by your physician, usually once daily with or without food. Do not crush or chew the tablet.

Benefits

• Effective and sustained blood pressure reduction.
• Reduces the risk of stroke and heart attack.
• Provides dual mechanism for comprehensive control.
• Improves overall cardiovascular health.
• Offers better control for resistant hypertension.
• Well-tolerated for long-term use.

Side Effects

• Dizziness
• Headache
• Fatigue
• Nausea
• Abdominal pain
• Peripheral edema (ankle swelling)
• Flushing
• Palpitations
• Somnolence
• Muscle cramps
• Increased urination
• Rash

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can increase the blood pressure-lowering effect and enhance side effects like dizziness.
• Pregnancy - Not recommended during pregnancy, especially in the second and third trimesters, due to potential fetal harm. Consult a doctor.
• Breastfeeding - Use with caution; small amounts may pass into breast milk. Consult your doctor before breastfeeding.
• Liver - Use with caution in patients with liver impairment; dosage adjustment may be necessary.
• Kidney - Use with caution in patients with kidney impairment; regular monitoring of kidney function is advised.
• Lung - Generally safe for patients with lung conditions, but always consult your doctor if you have pre-existing respiratory issues.

Disclaimer

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