TIGENICHE VIAL 1VAIL

About

Tigeniche VIAL contains an antibiotic from the glycylcycline class, primarily used for intravenous administration to treat serious bacterial infections. It exerts its bacteriostatic effect by inhibiting bacterial protein synthesis, thereby preventing bacterial growth and replication. This medication is particularly valuable in combating multi-drug resistant (MDR) Gram-positive, Gram-negative, and anaerobic bacteria, including strains like MRSA (Methicillin-resistant Staphylococcus aureus) and VRE (Vancomycin-resistant Enterococci), which are often challenging to treat with conventional antibiotics.

Tigeniche VIAL is indicated for complicated skin and skin structure infections and complicated intra-abdominal infections. Its broad spectrum of activity and efficacy against resistant pathogens make it a crucial option in hospital settings for patients with severe infections where other treatments may have failed or are inappropriate. Careful patient selection and monitoring for potential adverse effects are essential to ensure optimal therapeutic outcomes.

Uses

• Treatment of complicated skin and skin structure infections (cSSSI).
• Management of complicated intra-abdominal infections (cIAI).
• Therapy for community-acquired bacterial pneumonia (CABP).
• Effective against multi-drug resistant bacterial strains.

Directions For Use

Administer intravenously as directed by a healthcare professional. Dosage and duration depend on the infection's severity and patient response.

Benefits

• Effective against multi-drug resistant (MDR) pathogens.
• Broad spectrum of activity against Gram-positive, Gram-negative, and anaerobes.
• Useful for complicated skin and intra-abdominal infections.
• Provides an alternative for resistant bacterial infections.
• Good tissue penetration for target sites.
• Reduces the need for multiple antibiotic regimens.

Side Effects

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Elevated liver enzymes
• Pancreatitis
• Photosensitivity
• Injection site reactions
• Superinfection (e.g., C. difficile)
• Increased mortality in certain severe infections

Safety Measures

• Alcohol - Concurrent alcohol consumption may exacerbate gastrointestinal side effects. It is generally advisable to avoid alcohol during treatment.
• Pregnancy - Use during pregnancy is generally not recommended unless clearly necessary, as it may cause harm to the fetus. Consult a physician.
• Breastfeeding - Small amounts may pass into breast milk. Use with caution and monitor the infant for adverse effects. Consult a healthcare provider.
• Liver - Use with caution in patients with hepatic impairment. Dose adjustments may be necessary, and liver function should be closely monitored.
• Kidney - No dose adjustment is typically required for renal impairment, but caution is advised in severe cases.
• Lung - Generally safe for use in patients with lung conditions, but caution is advised in those with severe respiratory compromise or asthma due to potential allergic reactions.

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